APPLICATION OF THE TOTAL SCORE FOR THE CERAD BATTERY IN BULGARIAN DEMENTED AND CONTROL SUBJECTS
Background: The lack of a total numeric score of the CERAD neuropsychological battery may to some extent limit the possibilities for presenting the cognitive status and the degree of dementia. The objective of the present study is to apply the CERAD battery in a Bulgarian population of demented an...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Peytchinski Publishing
2017-10-01
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| Series: | Journal of IMAB |
| Subjects: | |
| Online Access: | http://www.journal-imab-bg.org/issues-2017/issue4/JofIMAB-2017-23-4p1718-1720.pdf |
| _version_ | 1818521143296917504 |
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| author | Ivan Dimitrov Ivan Aleksandrov Borislav Ivanov Ara Kaprelyan Mariana Arnaoudova |
| author_facet | Ivan Dimitrov Ivan Aleksandrov Borislav Ivanov Ara Kaprelyan Mariana Arnaoudova |
| author_sort | Ivan Dimitrov |
| collection | DOAJ |
| description | Background: The lack of a total numeric score of the CERAD neuropsychological battery may to some extent limit the possibilities for presenting the cognitive status and the degree of dementia.
The objective of the present study is to apply the CERAD battery in a Bulgarian population of demented and control subjects, to compute the total score for each participant, and to compare the performance of the two groups.
Methods: a total of 164 subjects, 134 patients with dementia and 30 controls were assessed using the Bulgarian version of the CERAD battery. The total score was calculated according to the method described by Chandler et al. Mean values were compared using independent samples t-test. ROC curves were built, and the area under the curve was calculated.
Results: The total score for the whole sample has a mean value of 63.45±20.56. After correction for age and education x=79.51±20.24. The total score is significantly lower in the demented subjects compared to the control group, for both raw and corrected score. The area under the ROC curve shows values of 0.988 and 0.986 before and after correction, respectively.
Conclusion: The statistically significant difference between the results of demented and control subjects, with and without correction for age and education, support the good applicability and high informative value of the instrument. The results of ROC analysis demonstrate the high value of the battery for diagnosing dementia. |
| first_indexed | 2024-12-11T01:47:09Z |
| format | Article |
| id | doaj.art-9eba74369e8a42deaff266c88e58b7e4 |
| institution | Directory Open Access Journal |
| issn | 1312-773X |
| language | English |
| last_indexed | 2024-12-11T01:47:09Z |
| publishDate | 2017-10-01 |
| publisher | Peytchinski Publishing |
| record_format | Article |
| series | Journal of IMAB |
| spelling | doaj.art-9eba74369e8a42deaff266c88e58b7e42022-12-22T01:24:52ZengPeytchinski PublishingJournal of IMAB1312-773X2017-10-012341718172010.5272/jimab.2017234.1718APPLICATION OF THE TOTAL SCORE FOR THE CERAD BATTERY IN BULGARIAN DEMENTED AND CONTROL SUBJECTSIvan Dimitrov0Ivan Aleksandrov1Borislav Ivanov2Ara Kaprelyan3Mariana Arnaoudova4Department of Nursing, Sliven Affiliate, Medical University - Varna, Bulgaria.Department of Nursing, Sliven Affiliate, Medical University - Varna, Bulgaria.Department of Clinical Medical Sciences, Medical University - Varna, Bulgaria.Department of Neurology and Neuroscience, Medical University - Varna, Bulgaria.Mariana ArnaoudovaBackground: The lack of a total numeric score of the CERAD neuropsychological battery may to some extent limit the possibilities for presenting the cognitive status and the degree of dementia. The objective of the present study is to apply the CERAD battery in a Bulgarian population of demented and control subjects, to compute the total score for each participant, and to compare the performance of the two groups. Methods: a total of 164 subjects, 134 patients with dementia and 30 controls were assessed using the Bulgarian version of the CERAD battery. The total score was calculated according to the method described by Chandler et al. Mean values were compared using independent samples t-test. ROC curves were built, and the area under the curve was calculated. Results: The total score for the whole sample has a mean value of 63.45±20.56. After correction for age and education x=79.51±20.24. The total score is significantly lower in the demented subjects compared to the control group, for both raw and corrected score. The area under the ROC curve shows values of 0.988 and 0.986 before and after correction, respectively. Conclusion: The statistically significant difference between the results of demented and control subjects, with and without correction for age and education, support the good applicability and high informative value of the instrument. The results of ROC analysis demonstrate the high value of the battery for diagnosing dementia.http://www.journal-imab-bg.org/issues-2017/issue4/JofIMAB-2017-23-4p1718-1720.pdfto compute the total score for each participantand to compare the performance of the two groups. Methods: a total of 164 subjects134 patients with dementia and 30 controls were assessed using the Bulgarian version of the CERAD battery. The total score was calculated according to the method described by Chandler et al. Mean values were compared using independent samples t-test. ROC curves were builtand the area under the curve was calculated. Results: The total score for the whole sample has a mean value of 63.45±20.56. After correction for age and education x=79.51±20.24. The total score is significantly lower in the demented subjects compared to the control groupfor both raw and corrected score. The area under the ROC curve shows values of 0.988 and 0.986 before and after correctionrespectively. Conclusion: The statistically significant difference between the results of demented and control subjectswith and without correction for age and educationCERADdementianeuropsychological assessmenttotal score |
| spellingShingle | Ivan Dimitrov Ivan Aleksandrov Borislav Ivanov Ara Kaprelyan Mariana Arnaoudova APPLICATION OF THE TOTAL SCORE FOR THE CERAD BATTERY IN BULGARIAN DEMENTED AND CONTROL SUBJECTS Journal of IMAB to compute the total score for each participant and to compare the performance of the two groups. Methods: a total of 164 subjects 134 patients with dementia and 30 controls were assessed using the Bulgarian version of the CERAD battery. The total score was calculated according to the method described by Chandler et al. Mean values were compared using independent samples t-test. ROC curves were built and the area under the curve was calculated. Results: The total score for the whole sample has a mean value of 63.45±20.56. After correction for age and education x=79.51±20.24. The total score is significantly lower in the demented subjects compared to the control group for both raw and corrected score. The area under the ROC curve shows values of 0.988 and 0.986 before and after correction respectively. Conclusion: The statistically significant difference between the results of demented and control subjects with and without correction for age and education CERAD dementia neuropsychological assessment total score |
| title | APPLICATION OF THE TOTAL SCORE FOR THE CERAD BATTERY IN BULGARIAN DEMENTED AND CONTROL SUBJECTS |
| title_full | APPLICATION OF THE TOTAL SCORE FOR THE CERAD BATTERY IN BULGARIAN DEMENTED AND CONTROL SUBJECTS |
| title_fullStr | APPLICATION OF THE TOTAL SCORE FOR THE CERAD BATTERY IN BULGARIAN DEMENTED AND CONTROL SUBJECTS |
| title_full_unstemmed | APPLICATION OF THE TOTAL SCORE FOR THE CERAD BATTERY IN BULGARIAN DEMENTED AND CONTROL SUBJECTS |
| title_short | APPLICATION OF THE TOTAL SCORE FOR THE CERAD BATTERY IN BULGARIAN DEMENTED AND CONTROL SUBJECTS |
| title_sort | application of the total score for the cerad battery in bulgarian demented and control subjects |
| topic | to compute the total score for each participant and to compare the performance of the two groups. Methods: a total of 164 subjects 134 patients with dementia and 30 controls were assessed using the Bulgarian version of the CERAD battery. The total score was calculated according to the method described by Chandler et al. Mean values were compared using independent samples t-test. ROC curves were built and the area under the curve was calculated. Results: The total score for the whole sample has a mean value of 63.45±20.56. After correction for age and education x=79.51±20.24. The total score is significantly lower in the demented subjects compared to the control group for both raw and corrected score. The area under the ROC curve shows values of 0.988 and 0.986 before and after correction respectively. Conclusion: The statistically significant difference between the results of demented and control subjects with and without correction for age and education CERAD dementia neuropsychological assessment total score |
| url | http://www.journal-imab-bg.org/issues-2017/issue4/JofIMAB-2017-23-4p1718-1720.pdf |
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