Unusual case of recurrent SMART (stroke-like migraine attacks after radiation therapy) syndrome
Stroke-like migraine attacks after radiation therapy (SMART) syndrome is a rare delayed complication of cerebral radiation therapy. A 53-year-old female initially presented with headache, confusion and left homonymous hemianopia. Her medical history was notable for cerebellar hemangioblastoma, which...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Annals of Indian Academy of Neurology |
| Subjects: | |
| Online Access: | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2016;volume=19;issue=3;spage=399;epage=401;aulast=Ramanathan |
| _version_ | 1811300639128420352 |
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| author | Ramnath Santosh Ramanathan Gayathri Sreedher Konark Malhotra Zain Guduru Deeksha Agarwal Mary Flaherty Timothy Leichliter Sandeep Rana |
| author_facet | Ramnath Santosh Ramanathan Gayathri Sreedher Konark Malhotra Zain Guduru Deeksha Agarwal Mary Flaherty Timothy Leichliter Sandeep Rana |
| author_sort | Ramnath Santosh Ramanathan |
| collection | DOAJ |
| description | Stroke-like migraine attacks after radiation therapy (SMART) syndrome is a rare delayed complication of cerebral radiation therapy. A 53-year-old female initially presented with headache, confusion and left homonymous hemianopia. Her medical history was notable for cerebellar hemangioblastoma, which was treated with radiation in 1987. Her initial brain MRI (magnetic resonance imaging) revealed cortical enhancement in the right temporo-parieto-occipital region. She improved spontaneously in 2 weeks and follow-up scan at 4 weeks revealed no residual enhancement or encephalomalacia. She presented 6 weeks later with aphasia. Her MRI brain revealed similar contrast-enhancing cortical lesion but on the left side. Repeat CSF studies was again negative other than elevated protein. She was treated conservatively and recovered completely within a week. Before diagnosing SMART syndrome, it is important to rule out tumor recurrence, encephalitis, posterior reversible encephalopathy syndrome (PRES) and stroke. Typically the condition is self-limiting, and gradually resolves. |
| first_indexed | 2024-04-13T06:55:12Z |
| format | Article |
| id | doaj.art-9ebb46f4ad734e648cffdc26829e89a0 |
| institution | Directory Open Access Journal |
| issn | 0972-2327 1998-3549 |
| language | English |
| last_indexed | 2024-04-13T06:55:12Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Indian Academy of Neurology |
| spelling | doaj.art-9ebb46f4ad734e648cffdc26829e89a02022-12-22T02:57:17ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492016-01-0119339940110.4103/0972-2327.168634Unusual case of recurrent SMART (stroke-like migraine attacks after radiation therapy) syndromeRamnath Santosh RamanathanGayathri SreedherKonark MalhotraZain GuduruDeeksha AgarwalMary FlahertyTimothy LeichliterSandeep RanaStroke-like migraine attacks after radiation therapy (SMART) syndrome is a rare delayed complication of cerebral radiation therapy. A 53-year-old female initially presented with headache, confusion and left homonymous hemianopia. Her medical history was notable for cerebellar hemangioblastoma, which was treated with radiation in 1987. Her initial brain MRI (magnetic resonance imaging) revealed cortical enhancement in the right temporo-parieto-occipital region. She improved spontaneously in 2 weeks and follow-up scan at 4 weeks revealed no residual enhancement or encephalomalacia. She presented 6 weeks later with aphasia. Her MRI brain revealed similar contrast-enhancing cortical lesion but on the left side. Repeat CSF studies was again negative other than elevated protein. She was treated conservatively and recovered completely within a week. Before diagnosing SMART syndrome, it is important to rule out tumor recurrence, encephalitis, posterior reversible encephalopathy syndrome (PRES) and stroke. Typically the condition is self-limiting, and gradually resolves.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2016;volume=19;issue=3;spage=399;epage=401;aulast=RamanathanMigrainesradiation therapySMART syndrome |
| spellingShingle | Ramnath Santosh Ramanathan Gayathri Sreedher Konark Malhotra Zain Guduru Deeksha Agarwal Mary Flaherty Timothy Leichliter Sandeep Rana Unusual case of recurrent SMART (stroke-like migraine attacks after radiation therapy) syndrome Annals of Indian Academy of Neurology Migraines radiation therapy SMART syndrome |
| title | Unusual case of recurrent SMART (stroke-like migraine attacks after radiation therapy) syndrome |
| title_full | Unusual case of recurrent SMART (stroke-like migraine attacks after radiation therapy) syndrome |
| title_fullStr | Unusual case of recurrent SMART (stroke-like migraine attacks after radiation therapy) syndrome |
| title_full_unstemmed | Unusual case of recurrent SMART (stroke-like migraine attacks after radiation therapy) syndrome |
| title_short | Unusual case of recurrent SMART (stroke-like migraine attacks after radiation therapy) syndrome |
| title_sort | unusual case of recurrent smart stroke like migraine attacks after radiation therapy syndrome |
| topic | Migraines radiation therapy SMART syndrome |
| url | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2016;volume=19;issue=3;spage=399;epage=401;aulast=Ramanathan |
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