The Role of the Metabolism of Zinc and Manganese Ions in Human Cancerogenesis

The Role of the Metabolism of Zinc and Manganese Ions in Human Cancerogenesis

Metal ion homeostasis is fundamental for life. Specifically, transition metals iron, manganese and zinc play a pivotal role in mitochondrial metabolism and energy generation, anti-oxidation defense, transcriptional regulation and the immune response. The misregulation of expression or mutations in i...

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Bibliographic Details
Main Authors: Julian Markovich Rozenberg, Margarita Kamynina, Maksim Sorokin, Marianna Zolotovskaia, Elena Koroleva, Kristina Kremenchutckaya, Alexander Gudkov, Anton Buzdin, Nicolas Borisov
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomedicines
Subjects:
zinc
manganese
transitional elements
microelements
cancer
tumorigenesis
Online Access:https://www.mdpi.com/2227-9059/10/5/1072

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