Development of in vitro and in vivo tools to evaluate the antiangiogenic potential of melatonin to neutralize the angiogenic effects of VEGF and breast cancer cells: CAM assay and 3D endothelial cell spheroids

Development of in vitro and in vivo tools to evaluate the antiangiogenic potential of melatonin to neutralize the angiogenic effects of VEGF and breast cancer cells: CAM assay and 3D endothelial cell spheroids

Melatonin is a molecule with different antitumor actions in breast cancer and has been described as an inhibitor of vascular endothelial growth factor (VEGF). Despite the recognition of the key role exerted by VEGF in tumor angiogenesis, limitations arise when developing models to test new antiangio...

Full description

Bibliographic Details
Main Authors: Aurora Laborda-Illanes, Lidia Sánchez-Alcoholado, Daniel Castellano-Castillo, Soukaina Boutriq, Isaac Plaza-Andrades, Lucía Aranega-Martín, Jesús Peralta-Linero, Emilio Alba, Alicia González-González, María Isabel Queipo-Ortuño
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Melatonin
VEGF
Endothelial cells
HUVEC
MCF-7
Spheroids
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222014305

Similar Items

Similar Items