Gene mutational analysis by NGS and its clinical significance in patients with myelodysplastic syndrome and acute myeloid leukemia

Gene mutational analysis by NGS and its clinical significance in patients with myelodysplastic syndrome and acute myeloid leukemia

Abstract Background In this study, we retrospectively summarized the differences of molecular gene mutations between MDS and AML patients, as well as the young and older age groups of MDS and AML patients. We also analyzed the response of newly diagnosed AML patients to standard DA or IA induction c...

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Bibliographic Details
Main Authors: Jifeng Yu, Yingmei Li, Tao Li, Yafei Li, Haizhou Xing, Hui Sun, Ling Sun, Dingming Wan, Yanfang Liu, Xinsheng Xie, Zhongxing Jiang
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Experimental Hematology & Oncology
Subjects:
Next generation sequencing
Myelodysplastic syndrome
Acute myeloid leukemia
Gene mutation
Induction chemotherapy
Clinical outcome
Online Access:https://doi.org/10.1186/s40164-019-0158-5

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