Endothelial Hyper-Permeability Induced by T1D Sera Can be Reversed by iNOS Inactivation

Endothelial Hyper-Permeability Induced by T1D Sera Can be Reversed by iNOS Inactivation

Type 1 Diabetes Mellitus (T1D) is associated with accelerated atherosclerosis that is responsible for high morbidity and mortality. Endothelial hyperpermeability, a feature of endothelial dysfunction, is an early step of atherogenesis since it favours intimal lipid uptake. Therefore, we tested endot...

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Bibliographic Details
Main Authors: Alessandra Cazzaniga, Roberta Scrimieri, Elisa Giani, Gian Vincenzo Zuccotti, Jeanette A. M. Maier
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
endothelial cells
permeability
diabetes mellitus type 1
nitric oxide
Online Access:https://www.mdpi.com/1422-0067/21/8/2798

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