Effect of cannabis use on PTSD treatment outcomes in veterans
Introduction: Researchers have found anandamide (an endocannabinoid) and cannabinoid type 1 receptor activation encourages extinction of aversive memories. Some theorize cannabinoids such as those in cannabis may provide a new treatment approach for PTSD, while others suggest it may worsen symptomol...
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| Format: | Article |
| Language: | English |
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American Association of Psychiatric Pharmacists
2021-07-01
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| Series: | Mental Health Clinician |
| Subjects: | |
| Online Access: | https://theijpt.org/doi/pdf/10.9740/mhc.2021.07.238 |
| _version_ | 1797383407341142016 |
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| author | Meagan Petersen, PharmD, BCPP Katherine Koller, PharmD, BCPP Craig Straley, PharmD, BCPP Ellen Reed, PharmD, BCPP |
| author_facet | Meagan Petersen, PharmD, BCPP Katherine Koller, PharmD, BCPP Craig Straley, PharmD, BCPP Ellen Reed, PharmD, BCPP |
| author_sort | Meagan Petersen, PharmD, BCPP |
| collection | DOAJ |
| description | Introduction: Researchers have found anandamide (an endocannabinoid) and cannabinoid type 1 receptor activation encourages extinction of aversive memories. Some theorize cannabinoids such as those in cannabis may provide a new treatment approach for PTSD, while others suggest it may worsen symptomology. The objective of the current study was to determine if cannabis use impacts the success of evidence-based intensive outpatient PTSD treatment in a veteran population.
Methods: A list of veterans enrolled in the Battle Creek Veterans' Affairs Medical Center outpatient PTSD Clinical Team Clinic between October 1st, 2008 and October 1st, 2016 was obtained, and a random sample was identified. Study participants were veterans aged 18 to 85 years, with at least 2 PTSD Checklist scores, and a diagnosis of PTSD. Data collected included mental health medications, type and number of evidence-based psychotherapy used, and presence of co-occurring behavioral health diagnoses. The cannabis use group was compared to the no-cannabis-use group, and differences in variables pertaining to the relative number of treatment successes and failures was evaluated for statistical and clinical significance.
Results: The majority of patients were white (87.1%) and male (95%). The success rate was similar between the cannabis and no-cannabis-use groups (51.9% and 51.4%, respectively).
Discussion: The current study did not show that a predominantly white male veteran sample diagnosed with PTSD differed in intensive PTSD treatment success or failure based on cannabis use. |
| first_indexed | 2024-03-08T21:20:30Z |
| format | Article |
| id | doaj.art-9ec6e97f125a4ce0b684745803eb2915 |
| institution | Directory Open Access Journal |
| issn | 2168-9709 |
| language | English |
| last_indexed | 2024-03-08T21:20:30Z |
| publishDate | 2021-07-01 |
| publisher | American Association of Psychiatric Pharmacists |
| record_format | Article |
| series | Mental Health Clinician |
| spelling | doaj.art-9ec6e97f125a4ce0b684745803eb29152023-12-21T11:42:19ZengAmerican Association of Psychiatric PharmacistsMental Health Clinician2168-97092021-07-0111423824210.9740/mhc.2021.07.238i2168-9709-11-4-238Effect of cannabis use on PTSD treatment outcomes in veteransMeagan Petersen, PharmD, BCPP0https://orcid.org/0000-0002-6683-2163Katherine Koller, PharmD, BCPP1https://orcid.org/0000-0003-2661-9429Craig Straley, PharmD, BCPP2https://orcid.org/0000-0001-5735-7973Ellen Reed, PharmD, BCPP3https://orcid.org/0000-0002-2727-95101 PGY-1 Psychiatric Pharmacy Resident, Battle Creek Veteran Affairs Medical Center, Battle Creek, Michigan2 Mental Health Clinical Pharmacy Specialist, Battle Creek Veteran Affairs Medical Center, Battle Creek, Michigan3 Professor, Pharmacy Practice Department, College of Pharmacy, Ferris State University, Big Rapids, Michigan4 Mental Health Clinical Pharmacy Specialist, Battle Creek Veteran Affairs Medical Center, Battle Creek, MichiganIntroduction: Researchers have found anandamide (an endocannabinoid) and cannabinoid type 1 receptor activation encourages extinction of aversive memories. Some theorize cannabinoids such as those in cannabis may provide a new treatment approach for PTSD, while others suggest it may worsen symptomology. The objective of the current study was to determine if cannabis use impacts the success of evidence-based intensive outpatient PTSD treatment in a veteran population. Methods: A list of veterans enrolled in the Battle Creek Veterans' Affairs Medical Center outpatient PTSD Clinical Team Clinic between October 1st, 2008 and October 1st, 2016 was obtained, and a random sample was identified. Study participants were veterans aged 18 to 85 years, with at least 2 PTSD Checklist scores, and a diagnosis of PTSD. Data collected included mental health medications, type and number of evidence-based psychotherapy used, and presence of co-occurring behavioral health diagnoses. The cannabis use group was compared to the no-cannabis-use group, and differences in variables pertaining to the relative number of treatment successes and failures was evaluated for statistical and clinical significance. Results: The majority of patients were white (87.1%) and male (95%). The success rate was similar between the cannabis and no-cannabis-use groups (51.9% and 51.4%, respectively). Discussion: The current study did not show that a predominantly white male veteran sample diagnosed with PTSD differed in intensive PTSD treatment success or failure based on cannabis use.https://theijpt.org/doi/pdf/10.9740/mhc.2021.07.238traumacannabisptsdposttraumatic stress disorder |
| spellingShingle | Meagan Petersen, PharmD, BCPP Katherine Koller, PharmD, BCPP Craig Straley, PharmD, BCPP Ellen Reed, PharmD, BCPP Effect of cannabis use on PTSD treatment outcomes in veterans Mental Health Clinician trauma cannabis ptsd posttraumatic stress disorder |
| title | Effect of cannabis use on PTSD treatment outcomes in veterans |
| title_full | Effect of cannabis use on PTSD treatment outcomes in veterans |
| title_fullStr | Effect of cannabis use on PTSD treatment outcomes in veterans |
| title_full_unstemmed | Effect of cannabis use on PTSD treatment outcomes in veterans |
| title_short | Effect of cannabis use on PTSD treatment outcomes in veterans |
| title_sort | effect of cannabis use on ptsd treatment outcomes in veterans |
| topic | trauma cannabis ptsd posttraumatic stress disorder |
| url | https://theijpt.org/doi/pdf/10.9740/mhc.2021.07.238 |
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