Impact of Repetitive DNA Elements on Snake Genome Biology and Evolution
The distinctive biology and unique evolutionary features of snakes make them fascinating model systems to elucidate how genomes evolve and how variation at the genomic level is interlinked with phenotypic-level evolution. Similar to other eukaryotic genomes, large proportions of snake genomes contai...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Cells |
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| Online Access: | https://www.mdpi.com/2073-4409/10/7/1707 |
| _version_ | 1797527396999495680 |
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| author | Syed Farhan Ahmad Worapong Singchat Thitipong Panthum Kornsorn Srikulnath |
| author_facet | Syed Farhan Ahmad Worapong Singchat Thitipong Panthum Kornsorn Srikulnath |
| author_sort | Syed Farhan Ahmad |
| collection | DOAJ |
| description | The distinctive biology and unique evolutionary features of snakes make them fascinating model systems to elucidate how genomes evolve and how variation at the genomic level is interlinked with phenotypic-level evolution. Similar to other eukaryotic genomes, large proportions of snake genomes contain repetitive DNA, including transposable elements (TEs) and satellite repeats. The importance of repetitive DNA and its structural and functional role in the snake genome, remain unclear. This review highlights the major types of repeats and their proportions in snake genomes, reflecting the high diversity and composition of snake repeats. We present snakes as an emerging and important model system for the study of repetitive DNA under the impact of sex and microchromosome evolution. We assemble evidence to show that certain repetitive elements in snakes are transcriptionally active and demonstrate highly dynamic lineage-specific patterns as repeat sequences. We hypothesize that particular TEs can trigger different genomic mechanisms that might contribute to driving adaptive evolution in snakes. Finally, we review emerging approaches that may be used to study the expression of repetitive elements in complex genomes, such as snakes. The specific aspects presented here will stimulate further discussion on the role of genomic repeats in shaping snake evolution. |
| first_indexed | 2024-03-10T09:43:18Z |
| format | Article |
| id | doaj.art-9ec8f81951474e9f91082b45d1d8b934 |
| institution | Directory Open Access Journal |
| issn | 2073-4409 |
| language | English |
| last_indexed | 2024-03-10T09:43:18Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cells |
| spelling | doaj.art-9ec8f81951474e9f91082b45d1d8b9342023-11-22T03:28:45ZengMDPI AGCells2073-44092021-07-01107170710.3390/cells10071707Impact of Repetitive DNA Elements on Snake Genome Biology and EvolutionSyed Farhan Ahmad0Worapong Singchat1Thitipong Panthum2Kornsorn Srikulnath3Animal Genomics and Bioresource Research Center (AGB Research Center), Faculty of Science, Kasetsart University, 50 Ngamwongwan, Chatuchak, Bangkok 10900, ThailandAnimal Genomics and Bioresource Research Center (AGB Research Center), Faculty of Science, Kasetsart University, 50 Ngamwongwan, Chatuchak, Bangkok 10900, ThailandAnimal Genomics and Bioresource Research Center (AGB Research Center), Faculty of Science, Kasetsart University, 50 Ngamwongwan, Chatuchak, Bangkok 10900, ThailandAnimal Genomics and Bioresource Research Center (AGB Research Center), Faculty of Science, Kasetsart University, 50 Ngamwongwan, Chatuchak, Bangkok 10900, ThailandThe distinctive biology and unique evolutionary features of snakes make them fascinating model systems to elucidate how genomes evolve and how variation at the genomic level is interlinked with phenotypic-level evolution. Similar to other eukaryotic genomes, large proportions of snake genomes contain repetitive DNA, including transposable elements (TEs) and satellite repeats. The importance of repetitive DNA and its structural and functional role in the snake genome, remain unclear. This review highlights the major types of repeats and their proportions in snake genomes, reflecting the high diversity and composition of snake repeats. We present snakes as an emerging and important model system for the study of repetitive DNA under the impact of sex and microchromosome evolution. We assemble evidence to show that certain repetitive elements in snakes are transcriptionally active and demonstrate highly dynamic lineage-specific patterns as repeat sequences. We hypothesize that particular TEs can trigger different genomic mechanisms that might contribute to driving adaptive evolution in snakes. Finally, we review emerging approaches that may be used to study the expression of repetitive elements in complex genomes, such as snakes. The specific aspects presented here will stimulate further discussion on the role of genomic repeats in shaping snake evolution.https://www.mdpi.com/2073-4409/10/7/1707reptileDNA repeatgenomechromosometransposable element |
| spellingShingle | Syed Farhan Ahmad Worapong Singchat Thitipong Panthum Kornsorn Srikulnath Impact of Repetitive DNA Elements on Snake Genome Biology and Evolution Cells reptile DNA repeat genome chromosome transposable element |
| title | Impact of Repetitive DNA Elements on Snake Genome Biology and Evolution |
| title_full | Impact of Repetitive DNA Elements on Snake Genome Biology and Evolution |
| title_fullStr | Impact of Repetitive DNA Elements on Snake Genome Biology and Evolution |
| title_full_unstemmed | Impact of Repetitive DNA Elements on Snake Genome Biology and Evolution |
| title_short | Impact of Repetitive DNA Elements on Snake Genome Biology and Evolution |
| title_sort | impact of repetitive dna elements on snake genome biology and evolution |
| topic | reptile DNA repeat genome chromosome transposable element |
| url | https://www.mdpi.com/2073-4409/10/7/1707 |
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