Effects of Polymer Blending on the Performance of a Subcutaneous Biodegradable Implant for HIV Pre-Exposure Prophylaxis (PrEP)

Effects of Polymer Blending on the Performance of a Subcutaneous Biodegradable Implant for HIV Pre-Exposure Prophylaxis (PrEP)

Long-acting (LA) HIV pre-exposure prophylaxis (PrEP) can mitigate challenges of adhering to daily or on-demand regimens of antiretrovirals (ARVs). We are developing a subcutaneous implant comprising polycaprolactone (PCL) for sustained delivery of ARVs for PrEP. Here we use tenofovir alafenamide (TA...

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Bibliographic Details
Main Authors: Linying Li, Christine Areson, Ariane van der Straten, Leah M. Johnson
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
poly(ε-caprolactone) (PCL)
biodegradable polymer
polymer blends
HIV pre-exposure prophylaxis (PrEP)
tenofovir alafenamide
subcutaneous implant
Online Access:https://www.mdpi.com/1422-0067/22/12/6529

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