Serratia marcescens Endocarditis: A Case Report and Literature Review
Serratia marcescens is a rarely implicated agent in endocarditis. We describe a case of a patient that underwent aortic and mitral valve replacement for Streptococcus agalactiae endocarditis. Four months later, he was readmitted with an ischemic stroke and fever. Physical examination and repetitive...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Ordem dos Médicos
2022-05-01
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| Series: | Acta Médica Portuguesa |
| Subjects: | |
| Online Access: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16377 |
| _version_ | 1811344770901999616 |
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| author | Ana Isabel Ferreira Fernando Oliveira e Silva Jorge Reis Marta Henriques Jorge Almeida |
| author_facet | Ana Isabel Ferreira Fernando Oliveira e Silva Jorge Reis Marta Henriques Jorge Almeida |
| author_sort | Ana Isabel Ferreira |
| collection | DOAJ |
| description | Serratia marcescens is a rarely implicated agent in endocarditis. We describe a case of a patient that underwent aortic and mitral valve replacement for Streptococcus agalactiae endocarditis. Four months later, he was readmitted with an ischemic stroke and fever. Physical examination and repetitive transthoracic echocardiogram were unremarkable. The initial blood cultures were negative. Due to sustained fever, vancomycin, gentamicin and piperacillin-tazobactam were initiated. On subsequent blood cultures, Serratia marcescens was isolated and antibiotics switched to ertapenem and gentamicin. In addition to cerebral emboli, a splenic embolus was found. The PET/CT revealed an abnormal hypercaptation in the mitral bioprosthesis. The patient was treated for six weeks. There are no current specific recommendations regarding the treatment of Serratia marcescens endocarditis. It is widely accepted that treatment should be prolonged and include a combination of antimicrobial agents. Morbidity and mortality are high, particularly when there’s the need for surgical replacement. In this case, however, the patient ended-up only requiring medical treatment due to the favourable response. |
| first_indexed | 2024-04-13T19:52:55Z |
| format | Article |
| id | doaj.art-9ecb59bf26cf482c8bf885f5714567b6 |
| institution | Directory Open Access Journal |
| issn | 0870-399X 1646-0758 |
| language | English |
| last_indexed | 2024-04-13T19:52:55Z |
| publishDate | 2022-05-01 |
| publisher | Ordem dos Médicos |
| record_format | Article |
| series | Acta Médica Portuguesa |
| spelling | doaj.art-9ecb59bf26cf482c8bf885f5714567b62022-12-22T02:32:27ZengOrdem dos MédicosActa Médica Portuguesa0870-399X1646-07582022-05-01351310.20344/amp.16377Serratia marcescens Endocarditis: A Case Report and Literature ReviewAna Isabel Ferreira0Fernando Oliveira e Silva1Jorge Reis2Marta Henriques3Jorge Almeida4Department of Internal Medicine. Centro Hospitalar Universitário de São João. Porto.Department of Infectious Diseases. Centro Hospitalar Universitário de São João. Porto.Department of Internal Medicine. Centro Hospitalar de Vila Nova de Gaia / Espinho. Gaia.Department of Hematology and Oncology. Centro Hospitalar Universitário de São João. Porto.Department of Internal Medicine. Centro Hospitalar Universitário de São João. Porto.Serratia marcescens is a rarely implicated agent in endocarditis. We describe a case of a patient that underwent aortic and mitral valve replacement for Streptococcus agalactiae endocarditis. Four months later, he was readmitted with an ischemic stroke and fever. Physical examination and repetitive transthoracic echocardiogram were unremarkable. The initial blood cultures were negative. Due to sustained fever, vancomycin, gentamicin and piperacillin-tazobactam were initiated. On subsequent blood cultures, Serratia marcescens was isolated and antibiotics switched to ertapenem and gentamicin. In addition to cerebral emboli, a splenic embolus was found. The PET/CT revealed an abnormal hypercaptation in the mitral bioprosthesis. The patient was treated for six weeks. There are no current specific recommendations regarding the treatment of Serratia marcescens endocarditis. It is widely accepted that treatment should be prolonged and include a combination of antimicrobial agents. Morbidity and mortality are high, particularly when there’s the need for surgical replacement. In this case, however, the patient ended-up only requiring medical treatment due to the favourable response.https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16377EndocarditisBacterialFeverHeart Valve ProsthesisPositron-Emission TomographySerratia marcescens |
| spellingShingle | Ana Isabel Ferreira Fernando Oliveira e Silva Jorge Reis Marta Henriques Jorge Almeida Serratia marcescens Endocarditis: A Case Report and Literature Review Acta Médica Portuguesa Endocarditis Bacterial Fever Heart Valve Prosthesis Positron-Emission Tomography Serratia marcescens |
| title | Serratia marcescens Endocarditis: A Case Report and Literature Review |
| title_full | Serratia marcescens Endocarditis: A Case Report and Literature Review |
| title_fullStr | Serratia marcescens Endocarditis: A Case Report and Literature Review |
| title_full_unstemmed | Serratia marcescens Endocarditis: A Case Report and Literature Review |
| title_short | Serratia marcescens Endocarditis: A Case Report and Literature Review |
| title_sort | serratia marcescens endocarditis a case report and literature review |
| topic | Endocarditis Bacterial Fever Heart Valve Prosthesis Positron-Emission Tomography Serratia marcescens |
| url | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16377 |
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