EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN»

A comparative study of the state of health of 110 women with allergopathology at the stage of pregnancy and their newborn children, with an assessment of the influence of factors burdening fetal fetal development and contributing to the implementation of allergopathology in the first months of life....

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Main Authors: L. A. Lityaeva, S. Y. Nosyreva
Format: Article
Language:Russian
Published: LLC "Diagnostics and Vaccines" 2017-12-01
Series:Детские инфекции (Москва)
Subjects:
Online Access:https://detinf.elpub.ru/jour/article/view/322
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author L. A. Lityaeva
S. Y. Nosyreva
author_facet L. A. Lityaeva
S. Y. Nosyreva
author_sort L. A. Lityaeva
collection DOAJ
description A comparative study of the state of health of 110 women with allergopathology at the stage of pregnancy and their newborn children, with an assessment of the influence of factors burdening fetal fetal development and contributing to the implementation of allergopathology in the first months of life.Trigger factors of disturbances in the formation of the intestinal microbiota, immune system and congenital decrease in the resistance of the child's organism — gestosis (c2 = 5.2, p = 0.022), Feto-placental insufficiency (c2 = 6.2, p = 0.012), chronic intrauterine fetal hypoxia (c2 = 5.7, p = 0.017), due to the presence in a woman with an allergic disease of combined somatic pathology and pathology of the genitals, malnutrition and microecological status.Such women should be classified as a high-risk group for intrauterine fetal sensitization and taken from the first days of pregnancy for primary prevention of allergopathology already at the stage of intrauterine development of the fetus.
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spelling doaj.art-9ecb67ae2839417ca88fd39fa7b6d29d2025-03-05T13:50:43ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072017-12-01164252910.22627/2072-8107-2017-16-4-25-29308EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN»L. A. Lityaeva0S. Y. Nosyreva1Orenburg State Medical University, OrenburgOrenburg State Medical University, OrenburgA comparative study of the state of health of 110 women with allergopathology at the stage of pregnancy and their newborn children, with an assessment of the influence of factors burdening fetal fetal development and contributing to the implementation of allergopathology in the first months of life.Trigger factors of disturbances in the formation of the intestinal microbiota, immune system and congenital decrease in the resistance of the child's organism — gestosis (c2 = 5.2, p = 0.022), Feto-placental insufficiency (c2 = 6.2, p = 0.012), chronic intrauterine fetal hypoxia (c2 = 5.7, p = 0.017), due to the presence in a woman with an allergic disease of combined somatic pathology and pathology of the genitals, malnutrition and microecological status.Such women should be classified as a high-risk group for intrauterine fetal sensitization and taken from the first days of pregnancy for primary prevention of allergopathology already at the stage of intrauterine development of the fetus.https://detinf.elpub.ru/jour/article/view/322pregnant womanrisk factorsallergopathologyintestinal microbiotainfant
spellingShingle L. A. Lityaeva
S. Y. Nosyreva
EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN»
Детские инфекции (Москва)
pregnant woman
risk factors
allergopathology
intestinal microbiota
infant
title EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN»
title_full EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN»
title_fullStr EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN»
title_full_unstemmed EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN»
title_short EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN»
title_sort epigenetic risk factors of fetal sensitization to allergens in the system mother fetus newborn
topic pregnant woman
risk factors
allergopathology
intestinal microbiota
infant
url https://detinf.elpub.ru/jour/article/view/322
work_keys_str_mv AT lalityaeva epigeneticriskfactorsoffetalsensitizationtoallergensinthesystemmotherfetusnewborn
AT synosyreva epigeneticriskfactorsoffetalsensitizationtoallergensinthesystemmotherfetusnewborn