EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN»
A comparative study of the state of health of 110 women with allergopathology at the stage of pregnancy and their newborn children, with an assessment of the influence of factors burdening fetal fetal development and contributing to the implementation of allergopathology in the first months of life....
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Format: | Article |
Language: | Russian |
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LLC "Diagnostics and Vaccines"
2017-12-01
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Series: | Детские инфекции (Москва) |
Subjects: | |
Online Access: | https://detinf.elpub.ru/jour/article/view/322 |
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author | L. A. Lityaeva S. Y. Nosyreva |
author_facet | L. A. Lityaeva S. Y. Nosyreva |
author_sort | L. A. Lityaeva |
collection | DOAJ |
description | A comparative study of the state of health of 110 women with allergopathology at the stage of pregnancy and their newborn children, with an assessment of the influence of factors burdening fetal fetal development and contributing to the implementation of allergopathology in the first months of life.Trigger factors of disturbances in the formation of the intestinal microbiota, immune system and congenital decrease in the resistance of the child's organism — gestosis (c2 = 5.2, p = 0.022), Feto-placental insufficiency (c2 = 6.2, p = 0.012), chronic intrauterine fetal hypoxia (c2 = 5.7, p = 0.017), due to the presence in a woman with an allergic disease of combined somatic pathology and pathology of the genitals, malnutrition and microecological status.Such women should be classified as a high-risk group for intrauterine fetal sensitization and taken from the first days of pregnancy for primary prevention of allergopathology already at the stage of intrauterine development of the fetus. |
first_indexed | 2024-04-10T03:25:40Z |
format | Article |
id | doaj.art-9ecb67ae2839417ca88fd39fa7b6d29d |
institution | Directory Open Access Journal |
issn | 2072-8107 |
language | Russian |
last_indexed | 2025-03-14T05:43:34Z |
publishDate | 2017-12-01 |
publisher | LLC "Diagnostics and Vaccines" |
record_format | Article |
series | Детские инфекции (Москва) |
spelling | doaj.art-9ecb67ae2839417ca88fd39fa7b6d29d2025-03-05T13:50:43ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072017-12-01164252910.22627/2072-8107-2017-16-4-25-29308EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN»L. A. Lityaeva0S. Y. Nosyreva1Orenburg State Medical University, OrenburgOrenburg State Medical University, OrenburgA comparative study of the state of health of 110 women with allergopathology at the stage of pregnancy and their newborn children, with an assessment of the influence of factors burdening fetal fetal development and contributing to the implementation of allergopathology in the first months of life.Trigger factors of disturbances in the formation of the intestinal microbiota, immune system and congenital decrease in the resistance of the child's organism — gestosis (c2 = 5.2, p = 0.022), Feto-placental insufficiency (c2 = 6.2, p = 0.012), chronic intrauterine fetal hypoxia (c2 = 5.7, p = 0.017), due to the presence in a woman with an allergic disease of combined somatic pathology and pathology of the genitals, malnutrition and microecological status.Such women should be classified as a high-risk group for intrauterine fetal sensitization and taken from the first days of pregnancy for primary prevention of allergopathology already at the stage of intrauterine development of the fetus.https://detinf.elpub.ru/jour/article/view/322pregnant womanrisk factorsallergopathologyintestinal microbiotainfant |
spellingShingle | L. A. Lityaeva S. Y. Nosyreva EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN» Детские инфекции (Москва) pregnant woman risk factors allergopathology intestinal microbiota infant |
title | EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN» |
title_full | EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN» |
title_fullStr | EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN» |
title_full_unstemmed | EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN» |
title_short | EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN» |
title_sort | epigenetic risk factors of fetal sensitization to allergens in the system mother fetus newborn |
topic | pregnant woman risk factors allergopathology intestinal microbiota infant |
url | https://detinf.elpub.ru/jour/article/view/322 |
work_keys_str_mv | AT lalityaeva epigeneticriskfactorsoffetalsensitizationtoallergensinthesystemmotherfetusnewborn AT synosyreva epigeneticriskfactorsoffetalsensitizationtoallergensinthesystemmotherfetusnewborn |