Supramammillary glutamate neurons are a key node of the arousal system
Supramammillary nucleus (SuM) neurons have been studied in the context of REM sleep but their possible role in mediating wakefulness is not known. Here the authors elucidate the distinct functional contributions of three subpopulations in the SuM on electrographical and behavioral arousal in mice us...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-01004-6 |
| _version_ | 1818751767643422720 |
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| author | Nigel P. Pedersen Loris Ferrari Anne Venner Joshua L. Wang Stephen B. G. Abbott Nina Vujovic Elda Arrigoni Clifford B. Saper Patrick M. Fuller |
| author_facet | Nigel P. Pedersen Loris Ferrari Anne Venner Joshua L. Wang Stephen B. G. Abbott Nina Vujovic Elda Arrigoni Clifford B. Saper Patrick M. Fuller |
| author_sort | Nigel P. Pedersen |
| collection | DOAJ |
| description | Supramammillary nucleus (SuM) neurons have been studied in the context of REM sleep but their possible role in mediating wakefulness is not known. Here the authors elucidate the distinct functional contributions of three subpopulations in the SuM on electrographical and behavioral arousal in mice using genetically targeted approaches. |
| first_indexed | 2024-12-18T04:40:48Z |
| format | Article |
| id | doaj.art-9ecd7e687f5343298ff44305203a1a25 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-18T04:40:48Z |
| publishDate | 2017-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-9ecd7e687f5343298ff44305203a1a252022-12-21T21:20:43ZengNature PortfolioNature Communications2041-17232017-11-018111610.1038/s41467-017-01004-6Supramammillary glutamate neurons are a key node of the arousal systemNigel P. Pedersen0Loris Ferrari1Anne Venner2Joshua L. Wang3Stephen B. G. Abbott4Nina Vujovic5Elda Arrigoni6Clifford B. Saper7Patrick M. Fuller8Department of Neurology and Epilepsy Service, Emory UniversityDepartment of Neurology, Beth Israel Deaconess Medical CenterDepartment of Neurology, Beth Israel Deaconess Medical CenterDepartment of Neurology, Beth Israel Deaconess Medical CenterDepartment of Neurology, Beth Israel Deaconess Medical CenterDivision of Sleep Medicine, Harvard Medical SchoolDepartment of Neurology, Beth Israel Deaconess Medical CenterDepartment of Neurology, Beth Israel Deaconess Medical CenterDepartment of Neurology, Beth Israel Deaconess Medical CenterSupramammillary nucleus (SuM) neurons have been studied in the context of REM sleep but their possible role in mediating wakefulness is not known. Here the authors elucidate the distinct functional contributions of three subpopulations in the SuM on electrographical and behavioral arousal in mice using genetically targeted approaches.https://doi.org/10.1038/s41467-017-01004-6 |
| spellingShingle | Nigel P. Pedersen Loris Ferrari Anne Venner Joshua L. Wang Stephen B. G. Abbott Nina Vujovic Elda Arrigoni Clifford B. Saper Patrick M. Fuller Supramammillary glutamate neurons are a key node of the arousal system Nature Communications |
| title | Supramammillary glutamate neurons are a key node of the arousal system |
| title_full | Supramammillary glutamate neurons are a key node of the arousal system |
| title_fullStr | Supramammillary glutamate neurons are a key node of the arousal system |
| title_full_unstemmed | Supramammillary glutamate neurons are a key node of the arousal system |
| title_short | Supramammillary glutamate neurons are a key node of the arousal system |
| title_sort | supramammillary glutamate neurons are a key node of the arousal system |
| url | https://doi.org/10.1038/s41467-017-01004-6 |
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