Flexible and accurate detection of genomic copy-number changes from aCGH.
Genomic DNA copy-number alterations (CNAs) are associated with complex diseases, including cancer: CNAs are indeed related to tumoral grade, metastasis, and patient survival. CNAs discovered from array-based comparative genomic hybridization (aCGH) data have been instrumental in identifying disease-...
Main Authors: | Oscar M Rueda, Ramón Díaz-Uriarte |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-06-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC1894821?pdf=render |
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