Red Ginger (Zingiber officinale var. Amarum) Infusion Increases Concentration of Luteinizing Hormone and Testosterone in Male Rats
Introduction: Herbal remedies have been developed as a complementary therapy to increase sex hormones. The administration of the ethanolic extract of red ginger (Zingiber officinale var. Amarum) has been shown to increase spermatogenic cells, motility and morphology of sperm in mice. However, the ef...
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| Format: | Article |
| Language: | English |
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Universitas Sultan Agung Semarang
2017-03-01
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| Series: | Sains Medika |
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| Online Access: | http://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/1174 |
| _version_ | 1817970001554964480 |
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| author | Alida Nihayah Taufiqurrahman Nasihun Israhnanto Isradji |
| author_facet | Alida Nihayah Taufiqurrahman Nasihun Israhnanto Isradji |
| author_sort | Alida Nihayah |
| collection | DOAJ |
| description | Introduction: Herbal remedies have been developed as a complementary therapy to increase sex hormones. The administration of the ethanolic extract of red ginger (Zingiber officinale var. Amarum) has been shown to increase spermatogenic cells, motility and morphology of sperm in mice. However, the effect of red ginger infusion on the level of testosterone and luteinizing hormone (LH) has not been done. Objective: to examine the effect of red ginger infusion on LH and testosterone levels of male Wistar rats.
Methods: The study was designed as an experimental post-test only control group design. Twenty four male Wistar rats of 200-250 g body weight aged + 3-4 months were divided into four groups. a control group (G-1) was given distilled water 2 ml/day. Group 2 (G-2), Group 3 (G-3), and group 4 (G-4) were treated with 10%, 20%, and 40% infusion by dissolving 2 ml of ginger in distilled water. On day 15, blood samples were taken and assayed for LH and testosterone.
Results: The one-way ANOVA test showed difference in levels of LH and testosterone between groups (p <0.001). Post Hoc LSD test results showed that the levels of LH of G-1 (0350) was significantly lower than that of G-2 (1082), G-3 (1 253), and G-4 (0923), p <0.005. While the levels of testosterone in the G-1 (0.2718) significantly lower than the G-2 (0.7797), G-3 (0.8285), and the G-4 (0.9142) (p <0.005).
Conclusion: red ginger infusion for 14 days can increase the levels of LH and testosterone in male rats. |
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| format | Article |
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| issn | 2085-1545 2339-093X |
| language | English |
| last_indexed | 2024-04-13T20:28:37Z |
| publishDate | 2017-03-01 |
| publisher | Universitas Sultan Agung Semarang |
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| series | Sains Medika |
| spelling | doaj.art-9ed4c1275eb7427a86a939082eeb172f2022-12-22T02:31:15ZengUniversitas Sultan Agung SemarangSains Medika2085-15452339-093X2017-03-0172545810.26532/sainsmed.v7i2.11741040Red Ginger (Zingiber officinale var. Amarum) Infusion Increases Concentration of Luteinizing Hormone and Testosterone in Male RatsAlida Nihayah0Taufiqurrahman Nasihun1Israhnanto Isradji2Post Graduate Program of Biomedical Sciences, Medical Faculty, Sultan Agung Islamic University *corresponding author: alidanihayah@gmail.comBiochemistry Department, Medical Faculty, Sultan Agung Islamic UniversityBiology Department, Medical Faculty, Sultan Agung Islamic UniversityIntroduction: Herbal remedies have been developed as a complementary therapy to increase sex hormones. The administration of the ethanolic extract of red ginger (Zingiber officinale var. Amarum) has been shown to increase spermatogenic cells, motility and morphology of sperm in mice. However, the effect of red ginger infusion on the level of testosterone and luteinizing hormone (LH) has not been done. Objective: to examine the effect of red ginger infusion on LH and testosterone levels of male Wistar rats. Methods: The study was designed as an experimental post-test only control group design. Twenty four male Wistar rats of 200-250 g body weight aged + 3-4 months were divided into four groups. a control group (G-1) was given distilled water 2 ml/day. Group 2 (G-2), Group 3 (G-3), and group 4 (G-4) were treated with 10%, 20%, and 40% infusion by dissolving 2 ml of ginger in distilled water. On day 15, blood samples were taken and assayed for LH and testosterone. Results: The one-way ANOVA test showed difference in levels of LH and testosterone between groups (p <0.001). Post Hoc LSD test results showed that the levels of LH of G-1 (0350) was significantly lower than that of G-2 (1082), G-3 (1 253), and G-4 (0923), p <0.005. While the levels of testosterone in the G-1 (0.2718) significantly lower than the G-2 (0.7797), G-3 (0.8285), and the G-4 (0.9142) (p <0.005). Conclusion: red ginger infusion for 14 days can increase the levels of LH and testosterone in male rats.http://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/1174LHTestosteroneinfusion of Red Ginger |
| spellingShingle | Alida Nihayah Taufiqurrahman Nasihun Israhnanto Isradji Red Ginger (Zingiber officinale var. Amarum) Infusion Increases Concentration of Luteinizing Hormone and Testosterone in Male Rats Sains Medika LH Testosterone infusion of Red Ginger |
| title | Red Ginger (Zingiber officinale var. Amarum) Infusion Increases Concentration of Luteinizing Hormone and Testosterone in Male Rats |
| title_full | Red Ginger (Zingiber officinale var. Amarum) Infusion Increases Concentration of Luteinizing Hormone and Testosterone in Male Rats |
| title_fullStr | Red Ginger (Zingiber officinale var. Amarum) Infusion Increases Concentration of Luteinizing Hormone and Testosterone in Male Rats |
| title_full_unstemmed | Red Ginger (Zingiber officinale var. Amarum) Infusion Increases Concentration of Luteinizing Hormone and Testosterone in Male Rats |
| title_short | Red Ginger (Zingiber officinale var. Amarum) Infusion Increases Concentration of Luteinizing Hormone and Testosterone in Male Rats |
| title_sort | red ginger zingiber officinale var amarum infusion increases concentration of luteinizing hormone and testosterone in male rats |
| topic | LH Testosterone infusion of Red Ginger |
| url | http://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/1174 |
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