Efficient and Robust <italic toggle="yes">Paramyxoviridae</italic> Reverse Genetics Systems

Efficient and Robust <italic toggle="yes">Paramyxoviridae</italic> Reverse Genetics Systems

ABSTRACT The notoriously low efficiency of Paramyxoviridae reverse genetics systems has posed a limiting barrier to the study of viruses in this family. Previous approaches to reverse genetics have utilized a wide variety of techniques to overcome the technical hurdles. Although robustness (i.e., th...

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Bibliographic Details
Main Authors: Shannon M. Beaty, Arnold Park, Sohui T. Won, Patrick Hong, Michael Lyons, Frederic Vigant, Alexander N. Freiberg, Benjamin R. tenOever, W. Paul Duprex, Benhur Lee
Format: Article
Language:English
Published: American Society for Microbiology 2017-04-01
Series:mSphere
Subjects:
paramyxovirus
reverse genetic analysis
ribozymes
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00376-16

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