Diagnostic accuracy of computed tomography in Wilm's tumour taking histopathology as gold standard in symptomatic renal masses at a tertiary care hospital, Karachi.
Background:Recent advances in imaging technology has made it possible to diagnose abdominal masses in the early stages along with accurate image-guided localization of biopsy sites. Contrast-enhanced Computed tomography (CECT) abdomen is one such imaging tool. This study aims to establish the diagno...
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| Format: | Article |
| Language: | English |
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Advance Educational Institute & Research Centre
2021-03-01
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| Series: | International Journal of Endorsing Health Science Research |
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| Online Access: | http://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/528/657 |
| _version_ | 1818873035946459136 |
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| author | Majid Shaikh Uzma Azmat Afaque Ali Nida Rafiq Uzma Omair |
| author_facet | Majid Shaikh Uzma Azmat Afaque Ali Nida Rafiq Uzma Omair |
| author_sort | Majid Shaikh |
| collection | DOAJ |
| description | Background:Recent advances in imaging technology has made it possible to diagnose abdominal masses in the early stages along with accurate image-guided localization of biopsy sites. Contrast-enhanced Computed tomography (CECT) abdomen is one such imaging tool. This study aims to establish the diagnostic accuracy of CT scans in detecting Wilm's tumour.Methodology:This descriptive cross-sectional study was conducted in the Department of Radiology, Sindh Institute of Urology and Transplantation (SIUT), Karachi, from 20-10-2018 till 04-20-2019. A total of 196 patients who were clinically suspected of renal masseswere included in this research project. CECT scan abdomen was acquired. The final diagnosis was based on histopathology.Results:Mean age in our study was 13.4±5.7 months. 104 (53.1%) were male, and 92 (46.9%) were female, respectively. Moreover, out of 196 patients, sensitivity, specificity, both the positive and negative predictive value along with diagnostic accuracy of CECT scan for diagnosis of Wilm's tumour by taking histopathology as the gold standard was found to be 93.4%, 91.8%, 95%, 89.4% and 92.8% respectively.Conclusion:It is concluded from the study results that the AbdominalCECT scan, despite its high radiation dose, is relevant and accurate in making a diagnosis of Wilms tumour, making it significantly helpful in early disease detection in poor resource settings such as ours where patients usually present late for treatment. |
| first_indexed | 2024-12-19T12:48:19Z |
| format | Article |
| id | doaj.art-9ed68d4476da4f78a1858d4f4264227e |
| institution | Directory Open Access Journal |
| issn | 2307-3748 2310-3841 |
| language | English |
| last_indexed | 2024-12-19T12:48:19Z |
| publishDate | 2021-03-01 |
| publisher | Advance Educational Institute & Research Centre |
| record_format | Article |
| series | International Journal of Endorsing Health Science Research |
| spelling | doaj.art-9ed68d4476da4f78a1858d4f4264227e2022-12-21T20:20:40ZengAdvance Educational Institute & Research CentreInternational Journal of Endorsing Health Science Research2307-37482310-38412021-03-0191889410.29052/IJEHSR.v9.i1.2021.88-94Diagnostic accuracy of computed tomography in Wilm's tumour taking histopathology as gold standard in symptomatic renal masses at a tertiary care hospital, Karachi.Majid Shaikh0Uzma Azmat1Afaque Ali2Nida Rafiq3Uzma Omair41Department of Radiology, Sindh Institute of urology and transplantation, Karachi-Pakistan.Department of Radiology and Imaging,Memon Medical Institute, Karachi-Pakistan.Department of Radiology, Shaukat Khanum Memorial Cancer Hospital,Karachi-Pakistan.Department of Radiology, Dow University Hospital, Karachi-Pakistan.Department of Radiology, Jinnah Postgraduate Medical Centre, Karachi-Pakistan.Background:Recent advances in imaging technology has made it possible to diagnose abdominal masses in the early stages along with accurate image-guided localization of biopsy sites. Contrast-enhanced Computed tomography (CECT) abdomen is one such imaging tool. This study aims to establish the diagnostic accuracy of CT scans in detecting Wilm's tumour.Methodology:This descriptive cross-sectional study was conducted in the Department of Radiology, Sindh Institute of Urology and Transplantation (SIUT), Karachi, from 20-10-2018 till 04-20-2019. A total of 196 patients who were clinically suspected of renal masseswere included in this research project. CECT scan abdomen was acquired. The final diagnosis was based on histopathology.Results:Mean age in our study was 13.4±5.7 months. 104 (53.1%) were male, and 92 (46.9%) were female, respectively. Moreover, out of 196 patients, sensitivity, specificity, both the positive and negative predictive value along with diagnostic accuracy of CECT scan for diagnosis of Wilm's tumour by taking histopathology as the gold standard was found to be 93.4%, 91.8%, 95%, 89.4% and 92.8% respectively.Conclusion:It is concluded from the study results that the AbdominalCECT scan, despite its high radiation dose, is relevant and accurate in making a diagnosis of Wilms tumour, making it significantly helpful in early disease detection in poor resource settings such as ours where patients usually present late for treatment.http://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/528/657wilm’s tumourcect scanhistopathologysymptomatic renal mass |
| spellingShingle | Majid Shaikh Uzma Azmat Afaque Ali Nida Rafiq Uzma Omair Diagnostic accuracy of computed tomography in Wilm's tumour taking histopathology as gold standard in symptomatic renal masses at a tertiary care hospital, Karachi. International Journal of Endorsing Health Science Research wilm’s tumour cect scan histopathology symptomatic renal mass |
| title | Diagnostic accuracy of computed tomography in Wilm's tumour taking histopathology as gold standard in symptomatic renal masses at a tertiary care hospital, Karachi. |
| title_full | Diagnostic accuracy of computed tomography in Wilm's tumour taking histopathology as gold standard in symptomatic renal masses at a tertiary care hospital, Karachi. |
| title_fullStr | Diagnostic accuracy of computed tomography in Wilm's tumour taking histopathology as gold standard in symptomatic renal masses at a tertiary care hospital, Karachi. |
| title_full_unstemmed | Diagnostic accuracy of computed tomography in Wilm's tumour taking histopathology as gold standard in symptomatic renal masses at a tertiary care hospital, Karachi. |
| title_short | Diagnostic accuracy of computed tomography in Wilm's tumour taking histopathology as gold standard in symptomatic renal masses at a tertiary care hospital, Karachi. |
| title_sort | diagnostic accuracy of computed tomography in wilm s tumour taking histopathology as gold standard in symptomatic renal masses at a tertiary care hospital karachi |
| topic | wilm’s tumour cect scan histopathology symptomatic renal mass |
| url | http://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/528/657 |
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