Computational and Experimental Evaluation of the Immune Response of Neoantigens for Personalized Vaccine Design

Computational and Experimental Evaluation of the Immune Response of Neoantigens for Personalized Vaccine Design

In the last few years, the importance of neoantigens in the development of personalized antitumor vaccines has increased remarkably. In order to study whether bioinformatic tools are effective in detecting neoantigens that generate an immune response, DNA samples from patients with cutaneous melanom...

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Bibliographic Details
Main Authors: Iker Malaina, Lorena Gonzalez-Melero, Luis Martínez, Aiala Salvador, Ana Sanchez-Diez, Aintzane Asumendi, Javier Margareto, Jose Carrasco-Pujante, Leire Legarreta, María Asunción García, Martín Blas Pérez-Pinilla, Rosa Izu, Ildefonso Martínez de la Fuente, Manoli Igartua, Santos Alonso, Rosa Maria Hernandez, María Dolores Boyano
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
bioinformatics
ex vivo
human leucocytic antigen
immunogenicity
nanoparticle
neoantigen
Online Access:https://www.mdpi.com/1422-0067/24/10/9024

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