Flaxseed dietary fibers lower cholesterol and increase fecal fat excretion, but magnitude of effect depend on food type
<p>Abstract</p> <p>Background</p> <p>Dietary fibers have been proposed to play a role in cardiovascular risk as well as body weight management. Flaxseeds are a good source of dietary fibers, and a large proportion of these are water-soluble viscous fibers.</p> <...
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| 格式: | Article |
| 語言: | English |
| 出版: |
BMC
2012-02-01
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| 叢編: | Nutrition & Metabolism |
| 主題: | |
| 在線閱讀: | http://www.nutritionandmetabolism.com/content/9/1/8 |
| _version_ | 1828437660964749312 |
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| author | Kristensen Mette Jensen Morten G Aarestrup Julie Petersen Kristina EN Søndergaard Lise Mikkelsen Mette S Astrup Arne |
| author_facet | Kristensen Mette Jensen Morten G Aarestrup Julie Petersen Kristina EN Søndergaard Lise Mikkelsen Mette S Astrup Arne |
| author_sort | Kristensen Mette |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Dietary fibers have been proposed to play a role in cardiovascular risk as well as body weight management. Flaxseeds are a good source of dietary fibers, and a large proportion of these are water-soluble viscous fibers.</p> <p>Method</p> <p>Here, we examine the effect of flaxseed dietary fibers in different food matrices on blood lipids and fecal excretion of fat and energy in a double-blind randomized crossover study with 17 subjects. Three different 7-d diets were tested: a low-fiber control diet (Control), a diet with flaxseed fiber drink (3/day) (Flax drink), and a diet with flaxseed fiber bread (3/day) (Flax bread). Total fat and energy excretion was measured in feces, blood samples were collected before and after each period, and appetite sensation registered 3 times daily before main meals.</p> <p>Results</p> <p>Compared to control, Flax drink lowered fasting total-cholesterol and LDL-cholesterol by 12 and 15%, respectively, (p < 0.01), whereas Flax bread only produced a reduction of 7 and 9%, respectively (p < 0.05). Fecal fat and energy excretion increased by 50 and 23% with Flax drink consumption compared to control (p < 0.05), but only fecal fat excretion was increased with Flax bread compared to control (p < 0.05).</p> <p>Conclusion</p> <p>Both Flax drink and Flax bread resulted in decreased plasma total and LDL-cholesterol and increased fat excretion, but the food matrix and/or processing may be of importance. Viscous flaxseed dietary fibers may be a useful tool for lowering blood cholesterol and potentially play a role in energy balance.</p> <p>Trial Registration</p> <p>ClinicalTrials.gov: <a href="http://www.clinicaltrials.gov/ct2/show/NCT00953004">NCT00953004</a></p> |
| first_indexed | 2024-12-10T19:49:25Z |
| format | Article |
| id | doaj.art-9edfbf1f19dc48a1b0f3a3b8e7b51f58 |
| institution | Directory Open Access Journal |
| issn | 1743-7075 |
| language | English |
| last_indexed | 2024-12-10T19:49:25Z |
| publishDate | 2012-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Nutrition & Metabolism |
| spelling | doaj.art-9edfbf1f19dc48a1b0f3a3b8e7b51f582022-12-22T01:35:48ZengBMCNutrition & Metabolism1743-70752012-02-0191810.1186/1743-7075-9-8Flaxseed dietary fibers lower cholesterol and increase fecal fat excretion, but magnitude of effect depend on food typeKristensen MetteJensen Morten GAarestrup JuliePetersen Kristina ENSøndergaard LiseMikkelsen Mette SAstrup Arne<p>Abstract</p> <p>Background</p> <p>Dietary fibers have been proposed to play a role in cardiovascular risk as well as body weight management. Flaxseeds are a good source of dietary fibers, and a large proportion of these are water-soluble viscous fibers.</p> <p>Method</p> <p>Here, we examine the effect of flaxseed dietary fibers in different food matrices on blood lipids and fecal excretion of fat and energy in a double-blind randomized crossover study with 17 subjects. Three different 7-d diets were tested: a low-fiber control diet (Control), a diet with flaxseed fiber drink (3/day) (Flax drink), and a diet with flaxseed fiber bread (3/day) (Flax bread). Total fat and energy excretion was measured in feces, blood samples were collected before and after each period, and appetite sensation registered 3 times daily before main meals.</p> <p>Results</p> <p>Compared to control, Flax drink lowered fasting total-cholesterol and LDL-cholesterol by 12 and 15%, respectively, (p < 0.01), whereas Flax bread only produced a reduction of 7 and 9%, respectively (p < 0.05). Fecal fat and energy excretion increased by 50 and 23% with Flax drink consumption compared to control (p < 0.05), but only fecal fat excretion was increased with Flax bread compared to control (p < 0.05).</p> <p>Conclusion</p> <p>Both Flax drink and Flax bread resulted in decreased plasma total and LDL-cholesterol and increased fat excretion, but the food matrix and/or processing may be of importance. Viscous flaxseed dietary fibers may be a useful tool for lowering blood cholesterol and potentially play a role in energy balance.</p> <p>Trial Registration</p> <p>ClinicalTrials.gov: <a href="http://www.clinicaltrials.gov/ct2/show/NCT00953004">NCT00953004</a></p>http://www.nutritionandmetabolism.com/content/9/1/8Flaxseeddietary fiberfat excretioncholesterol |
| spellingShingle | Kristensen Mette Jensen Morten G Aarestrup Julie Petersen Kristina EN Søndergaard Lise Mikkelsen Mette S Astrup Arne Flaxseed dietary fibers lower cholesterol and increase fecal fat excretion, but magnitude of effect depend on food type Nutrition & Metabolism Flaxseed dietary fiber fat excretion cholesterol |
| title | Flaxseed dietary fibers lower cholesterol and increase fecal fat excretion, but magnitude of effect depend on food type |
| title_full | Flaxseed dietary fibers lower cholesterol and increase fecal fat excretion, but magnitude of effect depend on food type |
| title_fullStr | Flaxseed dietary fibers lower cholesterol and increase fecal fat excretion, but magnitude of effect depend on food type |
| title_full_unstemmed | Flaxseed dietary fibers lower cholesterol and increase fecal fat excretion, but magnitude of effect depend on food type |
| title_short | Flaxseed dietary fibers lower cholesterol and increase fecal fat excretion, but magnitude of effect depend on food type |
| title_sort | flaxseed dietary fibers lower cholesterol and increase fecal fat excretion but magnitude of effect depend on food type |
| topic | Flaxseed dietary fiber fat excretion cholesterol |
| url | http://www.nutritionandmetabolism.com/content/9/1/8 |
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