Construction of an HLA Classifier for Early Diagnosis, Prognosis, and Recognition of Immunosuppression in Sepsis by Multiple Transcriptome Datasets

Construction of an HLA Classifier for Early Diagnosis, Prognosis, and Recognition of Immunosuppression in Sepsis by Multiple Transcriptome Datasets

Background: Sepsis is a clinical syndrome, due to a dysregulated inflammatory response to infection. Accumulating evidence shows that human leukocyte antigen (HLA) genes play a key role in the immune responses to sepsis. Nevertheless, the effects of HLA genes in sepsis have still not been comprehens...

Полное описание

Библиографические подробности
Главные авторы: Zhen Chen, Rui Chen, Yangpeng Ou, Jianhai Lu, Qianhua Jiang, Genglong Liu, Liping Wang, Yayun Liu, Zhujiang Zhou, Ben Yang, Liuer Zuo
Формат: Статья
Язык:English
Опубликовано: Frontiers Media S.A. 2022-05-01
Серии:Frontiers in Physiology
Предметы:
sepsis
HLA genes
immune infiltration
immunosuppression
model
Online-ссылка:https://www.frontiersin.org/articles/10.3389/fphys.2022.870657/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.870657/full

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