Tissue-Nonspecific Alkaline Phosphatase—A Gatekeeper of Physiological Conditions in Health and a Modulator of Biological Environments in Disease

Tissue-Nonspecific Alkaline Phosphatase—A Gatekeeper of Physiological Conditions in Health and a Modulator of Biological Environments in Disease

Tissue-nonspecific alkaline phosphatase (TNAP) is a ubiquitously expressed enzyme that is best known for its role during mineralization processes in bones and skeleton. The enzyme metabolizes phosphate compounds like inorganic pyrophosphate and pyridoxal-5′-phosphate to provide, among others, inorga...

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Bibliographic Details
Main Authors:	Daniel Liedtke, Christine Hofmann, Franz Jakob, Eva Klopocki, Stephanie Graser
Format:	Article
Language:	English
Published:	MDPI AG 2020-12-01
Series:	Biomolecules
Subjects:	TNAP hypophosphatasia HPP zebrafish mineralization <i>ALPL</i>
Online Access:	https://www.mdpi.com/2218-273X/10/12/1648

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