Polar Ejection Forces Promote the Conversion from Lateral to End-on Kinetochore-Microtubule Attachments on Mono-oriented Chromosomes

Polar Ejection Forces Promote the Conversion from Lateral to End-on Kinetochore-Microtubule Attachments on Mono-oriented Chromosomes

Chromosome bi-orientation occurs after conversion of initial lateral attachments between kinetochores and spindle microtubules into stable end-on attachments near the cell equator. After bi-orientation, chromosomes experience tension from spindle forces, which plays a key role in the stabilization o...

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Bibliographic Details
Main Authors: Danica Drpic, António J. Pereira, Marin Barisic, Thomas J. Maresca, Helder Maiato
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Cell Reports
Subjects:
chromokinesins
kinetochore
mitosis
mitosis with unreplicated genomes
spindle assembly checkpoint
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715008645

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