Engineering metal-organic framework nanoparticles trigger pyroptosis to boost colon cancer immunotherapy

Engineering metal-organic framework nanoparticles trigger pyroptosis to boost colon cancer immunotherapy

Pyroptosis, which is a novel form of immunogenic cell death, plays a vital role in antitumor therapy. Zirconium-based metal–organic frameworks (Zr-MOFs) have been applied in various antitumor treatments. However, the intrinsic role of these frameworks in pyroptosis has yet to be determined. Here, a...

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Bibliographic Details
Main Authors: Xiang Wang, Xufeng Lu, Xinxin Yang, Bingzi Zhu, Wenhai Deng, Qinfan Ye, Binglong Bai, Danna Liang, Bingxuan Shao, Yingpeng Huang, Tao You, Weiteng Zhang, Weijian Sun, Xian Shen
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Materials & Design
Subjects:
Zr-MOF
DOX
Colon cancer
Pyroptosis
PD-1
Immunotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127524001035

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