Intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model
As one of the most common diseases in pediatric surgery, an inguinal hernia is usually diagnosed by medical experts based on clinical data collected from magnetic resonance imaging (MRI), computed tomography (CT), or B-ultrasound. The parameters of blood routine examination, such as white blood cell...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-03-01
|
| Series: | Frontiers in Physiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2023.1105891/full |
| _version_ | 1797871445709160448 |
|---|---|
| author | Zhi-Wen Liu Gang Chen Chao-Fan Dong Wang-Ren Qiu Shou-Hua Zhang |
| author_facet | Zhi-Wen Liu Gang Chen Chao-Fan Dong Wang-Ren Qiu Shou-Hua Zhang |
| author_sort | Zhi-Wen Liu |
| collection | DOAJ |
| description | As one of the most common diseases in pediatric surgery, an inguinal hernia is usually diagnosed by medical experts based on clinical data collected from magnetic resonance imaging (MRI), computed tomography (CT), or B-ultrasound. The parameters of blood routine examination, such as white blood cell count and platelet count, are often used as diagnostic indicators of intestinal necrosis. Based on the medical numerical data on blood routine examination parameters and liver and kidney function parameters, this paper used machine learning algorithm to assist the diagnosis of intestinal necrosis in children with inguinal hernia before operation. In the work, we used clinical data consisting of 3,807 children with inguinal hernia symptoms and 170 children with intestinal necrosis and perforation caused by the disease. Three different models were constructed according to the blood routine examination and liver and kidney function. Some missing values were replaced by using the RIN-3M (median, mean, or mode region random interpolation) method according to the actual necessity, and the ensemble learning based on the voting principle was used to deal with the imbalanced datasets. The model trained after feature selection yielded satisfactory results with an accuracy of 86.43%, sensitivity of 84.34%, specificity of 96.89%, and AUC value of 0.91. Therefore, the proposed methods may be a potential idea for auxiliary diagnosis of inguinal hernia in children. |
| first_indexed | 2024-04-10T00:44:11Z |
| format | Article |
| id | doaj.art-9eecab2cdb75481dab8ec35e233c222f |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-04-10T00:44:11Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-9eecab2cdb75481dab8ec35e233c222f2023-03-14T04:25:11ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2023-03-011410.3389/fphys.2023.11058911105891Intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification modelZhi-Wen Liu0Gang Chen1Chao-Fan Dong2Wang-Ren Qiu3Shou-Hua Zhang4Department of General Surgery, Jiangxi Provincial Children’s Hospital, Nanchang, ChinaComputer Department, Jing-De-Zhen Jingdezhen Ceramic Institute, Jingdezhen, ChinaDepartment of General Surgery, Jingdezhen No. 1 People’s Hospital, Jingdezhen, ChinaComputer Department, Jing-De-Zhen Jingdezhen Ceramic Institute, Jingdezhen, ChinaDepartment of General Surgery, Jiangxi Provincial Children’s Hospital, Nanchang, ChinaAs one of the most common diseases in pediatric surgery, an inguinal hernia is usually diagnosed by medical experts based on clinical data collected from magnetic resonance imaging (MRI), computed tomography (CT), or B-ultrasound. The parameters of blood routine examination, such as white blood cell count and platelet count, are often used as diagnostic indicators of intestinal necrosis. Based on the medical numerical data on blood routine examination parameters and liver and kidney function parameters, this paper used machine learning algorithm to assist the diagnosis of intestinal necrosis in children with inguinal hernia before operation. In the work, we used clinical data consisting of 3,807 children with inguinal hernia symptoms and 170 children with intestinal necrosis and perforation caused by the disease. Three different models were constructed according to the blood routine examination and liver and kidney function. Some missing values were replaced by using the RIN-3M (median, mean, or mode region random interpolation) method according to the actual necessity, and the ensemble learning based on the voting principle was used to deal with the imbalanced datasets. The model trained after feature selection yielded satisfactory results with an accuracy of 86.43%, sensitivity of 84.34%, specificity of 96.89%, and AUC value of 0.91. Therefore, the proposed methods may be a potential idea for auxiliary diagnosis of inguinal hernia in children.https://www.frontiersin.org/articles/10.3389/fphys.2023.1105891/fullimbalanced datamedical numerical datapostoperative diagnosismachine learningintelligent assistant diagnosis |
| spellingShingle | Zhi-Wen Liu Gang Chen Chao-Fan Dong Wang-Ren Qiu Shou-Hua Zhang Intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model Frontiers in Physiology imbalanced data medical numerical data postoperative diagnosis machine learning intelligent assistant diagnosis |
| title | Intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model |
| title_full | Intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model |
| title_fullStr | Intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model |
| title_full_unstemmed | Intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model |
| title_short | Intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model |
| title_sort | intelligent assistant diagnosis for pediatric inguinal hernia based on a multilayer and unbalanced classification model |
| topic | imbalanced data medical numerical data postoperative diagnosis machine learning intelligent assistant diagnosis |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2023.1105891/full |
| work_keys_str_mv | AT zhiwenliu intelligentassistantdiagnosisforpediatricinguinalherniabasedonamultilayerandunbalancedclassificationmodel AT gangchen intelligentassistantdiagnosisforpediatricinguinalherniabasedonamultilayerandunbalancedclassificationmodel AT chaofandong intelligentassistantdiagnosisforpediatricinguinalherniabasedonamultilayerandunbalancedclassificationmodel AT wangrenqiu intelligentassistantdiagnosisforpediatricinguinalherniabasedonamultilayerandunbalancedclassificationmodel AT shouhuazhang intelligentassistantdiagnosisforpediatricinguinalherniabasedonamultilayerandunbalancedclassificationmodel |