Assessment of Image Quality and Lesion Detectability With Digital PET/CT System
Purpose: The aim of this study was to assess image quality and lesion detectability acquired with a digital Positron Emission Tomography/Computed Tomography (PET/CT) Siemens Biograph Vision 600 system.Material and Methods: Consecutive patients who underwent a FDG PET/CT during the first week of use...
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Frontiers Media S.A.
2021-02-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2021.629096/full |
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| author | Olivier Delcroix David Bourhis David Bourhis David Bourhis Nathalie Keromnes Philippe Robin Philippe Robin Philippe Robin Pierre-Yves Le Roux Pierre-Yves Le Roux Pierre-Yves Le Roux Ronan Abgral Ronan Abgral Ronan Abgral Pierre-Yves Salaun Pierre-Yves Salaun Pierre-Yves Salaun Solène Querellou Solène Querellou Solène Querellou |
| author_facet | Olivier Delcroix David Bourhis David Bourhis David Bourhis Nathalie Keromnes Philippe Robin Philippe Robin Philippe Robin Pierre-Yves Le Roux Pierre-Yves Le Roux Pierre-Yves Le Roux Ronan Abgral Ronan Abgral Ronan Abgral Pierre-Yves Salaun Pierre-Yves Salaun Pierre-Yves Salaun Solène Querellou Solène Querellou Solène Querellou |
| author_sort | Olivier Delcroix |
| collection | DOAJ |
| description | Purpose: The aim of this study was to assess image quality and lesion detectability acquired with a digital Positron Emission Tomography/Computed Tomography (PET/CT) Siemens Biograph Vision 600 system.Material and Methods: Consecutive patients who underwent a FDG PET/CT during the first week of use of a digital PET/CT (Siemens Biograph Vision 600) at the nuclear medicine department of the university hospital of Brest were analyzed. PET were realized using list mode acquisition. For all patients, 4 datasets were reconstructed. We determined, according to phantom measurements, an equivalent time acquisition/reconstruction parameters pair of the digital PET/CT corresponding to an analog PET/CT image quality (“analog-like”) as reference dataset. We compared the reference dataset with 3 others digital PET/CT reconstruction parameters, allowing a decrease of emission duration: 60, 90, and 120 s per bed position. Three nuclear medicine physicians evaluated independently, for each dataset, overall image quality [Maximal Intensity Projection (MIP), noise, sharpness] using a 4-point scale. Physicians assessed also lesion detection capability by reporting new visible lesions on each digital datasets with their confidence level in comparison with analog-like dataset.Results: Ninety-eight patients were analyzed. Image quality of MIP (IQMIP), sharpness (IQSHARPNESS), and noise (IQNOISE) of all digital datasets (60, 90, and 120 s) were better than those evaluated with analog-like reconstruction. Moreover, digital PET/CT system improved IQMIP, IQNOISE, and IQSHARPNESS whatever the BMI. Lesion detection capability and confidence level were higher for 60, 90, 120 s per bed position, respectively, than for analog-like images.Conclusion: Our study demonstrated an improvement of image quality and lesion detectability with a digital PET/CT system. |
| first_indexed | 2024-12-14T11:17:34Z |
| format | Article |
| id | doaj.art-9eecbc6457494c138090777326711759 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-12-14T11:17:34Z |
| publishDate | 2021-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-9eecbc6457494c1380907773267117592022-12-21T23:03:56ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2021-02-01810.3389/fmed.2021.629096629096Assessment of Image Quality and Lesion Detectability With Digital PET/CT SystemOlivier Delcroix0David Bourhis1David Bourhis2David Bourhis3Nathalie Keromnes4Philippe Robin5Philippe Robin6Philippe Robin7Pierre-Yves Le Roux8Pierre-Yves Le Roux9Pierre-Yves Le Roux10Ronan Abgral11Ronan Abgral12Ronan Abgral13Pierre-Yves Salaun14Pierre-Yves Salaun15Pierre-Yves Salaun16Solène Querellou17Solène Querellou18Solène Querellou19Nuclear Medicine Department, Brest University Hospital, Brest, FranceNuclear Medicine Department, Brest University Hospital, Brest, FranceEA 3878 GETBO IFR, Brest, FranceUniversity of Bretagne Occidental, Brest, FranceNuclear Medicine Department, Brest University Hospital, Brest, FranceNuclear Medicine Department, Brest University Hospital, Brest, FranceEA 3878 GETBO IFR, Brest, FranceUniversity of Bretagne Occidental, Brest, FranceNuclear Medicine Department, Brest University Hospital, Brest, FranceEA 3878 GETBO IFR, Brest, FranceUniversity of Bretagne Occidental, Brest, FranceNuclear Medicine Department, Brest University Hospital, Brest, FranceEA 3878 GETBO IFR, Brest, FranceUniversity of Bretagne Occidental, Brest, FranceNuclear Medicine Department, Brest University Hospital, Brest, FranceEA 3878 GETBO IFR, Brest, FranceUniversity of Bretagne Occidental, Brest, FranceNuclear Medicine Department, Brest University Hospital, Brest, FranceEA 3878 GETBO IFR, Brest, FranceUniversity of Bretagne Occidental, Brest, FrancePurpose: The aim of this study was to assess image quality and lesion detectability acquired with a digital Positron Emission Tomography/Computed Tomography (PET/CT) Siemens Biograph Vision 600 system.Material and Methods: Consecutive patients who underwent a FDG PET/CT during the first week of use of a digital PET/CT (Siemens Biograph Vision 600) at the nuclear medicine department of the university hospital of Brest were analyzed. PET were realized using list mode acquisition. For all patients, 4 datasets were reconstructed. We determined, according to phantom measurements, an equivalent time acquisition/reconstruction parameters pair of the digital PET/CT corresponding to an analog PET/CT image quality (“analog-like”) as reference dataset. We compared the reference dataset with 3 others digital PET/CT reconstruction parameters, allowing a decrease of emission duration: 60, 90, and 120 s per bed position. Three nuclear medicine physicians evaluated independently, for each dataset, overall image quality [Maximal Intensity Projection (MIP), noise, sharpness] using a 4-point scale. Physicians assessed also lesion detection capability by reporting new visible lesions on each digital datasets with their confidence level in comparison with analog-like dataset.Results: Ninety-eight patients were analyzed. Image quality of MIP (IQMIP), sharpness (IQSHARPNESS), and noise (IQNOISE) of all digital datasets (60, 90, and 120 s) were better than those evaluated with analog-like reconstruction. Moreover, digital PET/CT system improved IQMIP, IQNOISE, and IQSHARPNESS whatever the BMI. Lesion detection capability and confidence level were higher for 60, 90, 120 s per bed position, respectively, than for analog-like images.Conclusion: Our study demonstrated an improvement of image quality and lesion detectability with a digital PET/CT system.https://www.frontiersin.org/articles/10.3389/fmed.2021.629096/fullanalog detectorsPET/CTclinical evaluationimage qualitySiPM |
| spellingShingle | Olivier Delcroix David Bourhis David Bourhis David Bourhis Nathalie Keromnes Philippe Robin Philippe Robin Philippe Robin Pierre-Yves Le Roux Pierre-Yves Le Roux Pierre-Yves Le Roux Ronan Abgral Ronan Abgral Ronan Abgral Pierre-Yves Salaun Pierre-Yves Salaun Pierre-Yves Salaun Solène Querellou Solène Querellou Solène Querellou Assessment of Image Quality and Lesion Detectability With Digital PET/CT System Frontiers in Medicine analog detectors PET/CT clinical evaluation image quality SiPM |
| title | Assessment of Image Quality and Lesion Detectability With Digital PET/CT System |
| title_full | Assessment of Image Quality and Lesion Detectability With Digital PET/CT System |
| title_fullStr | Assessment of Image Quality and Lesion Detectability With Digital PET/CT System |
| title_full_unstemmed | Assessment of Image Quality and Lesion Detectability With Digital PET/CT System |
| title_short | Assessment of Image Quality and Lesion Detectability With Digital PET/CT System |
| title_sort | assessment of image quality and lesion detectability with digital pet ct system |
| topic | analog detectors PET/CT clinical evaluation image quality SiPM |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2021.629096/full |
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