Childhood tuberculosis: management and treatment outcomes among children in Northwest Ethiopia: a cross-sectional study
Introduction: childhood tuberculosis (TB) treatment is becoming a major challenge in the TB control efforts of the Ethiopian health system. This study assessed childhood tuberculosis management, and treatment outcomes among children who completed anti-TB treatment in Northwest Ethiopia. Meth...
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| Format: | Article |
| Language: | English |
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The Pan African Medical Journal
2017-05-01
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| Series: | The Pan African Medical Journal |
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https://www.panafrican-med-journal.com/content/article/27/25/pdf/25.pdf
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| _version_ | 1818261886325489664 |
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| author | Zemene Tigabu Kebede Belaynew Wasie Taye Yohannes Hailu Matebe |
| author_facet | Zemene Tigabu Kebede Belaynew Wasie Taye Yohannes Hailu Matebe |
| author_sort | Zemene Tigabu Kebede |
| collection | DOAJ |
| description | Introduction: childhood tuberculosis (TB) treatment is becoming a major challenge in the TB control efforts of the Ethiopian health system. This study assessed childhood tuberculosis management, and treatment outcomes among children who completed anti-TB treatment in Northwest Ethiopia. Methods: a cross-sectional study was conducted among children who completed their anti-TB treatment in Gondar University Referral Hospital and 6 satellite health centers. Data from each child with tuberculosis were obtained from review of medical records. P-values 0.05 were considered statistically significant. Results: the commonest method of childhood TB diagnosis was clinical assessment combined with chest x-ray (48.5%). Absence of compliance with TB treatment guideline (98.7%), providing inadequate anti-TB regimen (1.8%), and poor adherence to treatment (22.5%) were challenges in management of childhood tuberculosis. Treatment success rate was 78.9%. In the bivariate regression, factors associated with TB treatment outcomes were permanent residence (OR=8.3, 95%CI: 4.1, 16.7), antiretroviral therapy (OR=4.5, 95%CI: 1.2, 16), and adherence to treatment (p = 0.001). After controlling for confounders, adherence to anti-TB treatment (OR=0.003, 95% CI: 0.001, 0.02) was independent predictor of treatment success. Conclusion: anti-tuberculosis treatment success rate was still low among children in Northwest Ethiopia. The health centers and hospital shall enhance strong follow-up of children on anti-tuberculosis treatment to improve treatment success with focus on rural children. |
| first_indexed | 2024-12-12T18:54:21Z |
| format | Article |
| id | doaj.art-9eef8513fb9e4568b8e5ffe2f65134fd |
| institution | Directory Open Access Journal |
| issn | 1937-8688 1937-8688 |
| language | English |
| last_indexed | 2024-12-12T18:54:21Z |
| publishDate | 2017-05-01 |
| publisher | The Pan African Medical Journal |
| record_format | Article |
| series | The Pan African Medical Journal |
| spelling | doaj.art-9eef8513fb9e4568b8e5ffe2f65134fd2022-12-22T00:15:17ZengThe Pan African Medical JournalThe Pan African Medical Journal1937-86881937-86882017-05-01272510.11604/pamj.2017.27.25.1012010120Childhood tuberculosis: management and treatment outcomes among children in Northwest Ethiopia: a cross-sectional studyZemene Tigabu Kebede0Belaynew Wasie Taye1Yohannes Hailu Matebe2 Department of Paediatrics, College of Medicine, University of Gondar, Ethiopia School of Public Health, College of Medicine, Bahir Dar University, Ethiopia Department of Paediatrics, College of Medicine, University of Gondar, Ethiopia Introduction: childhood tuberculosis (TB) treatment is becoming a major challenge in the TB control efforts of the Ethiopian health system. This study assessed childhood tuberculosis management, and treatment outcomes among children who completed anti-TB treatment in Northwest Ethiopia. Methods: a cross-sectional study was conducted among children who completed their anti-TB treatment in Gondar University Referral Hospital and 6 satellite health centers. Data from each child with tuberculosis were obtained from review of medical records. P-values 0.05 were considered statistically significant. Results: the commonest method of childhood TB diagnosis was clinical assessment combined with chest x-ray (48.5%). Absence of compliance with TB treatment guideline (98.7%), providing inadequate anti-TB regimen (1.8%), and poor adherence to treatment (22.5%) were challenges in management of childhood tuberculosis. Treatment success rate was 78.9%. In the bivariate regression, factors associated with TB treatment outcomes were permanent residence (OR=8.3, 95%CI: 4.1, 16.7), antiretroviral therapy (OR=4.5, 95%CI: 1.2, 16), and adherence to treatment (p = 0.001). After controlling for confounders, adherence to anti-TB treatment (OR=0.003, 95% CI: 0.001, 0.02) was independent predictor of treatment success. Conclusion: anti-tuberculosis treatment success rate was still low among children in Northwest Ethiopia. The health centers and hospital shall enhance strong follow-up of children on anti-tuberculosis treatment to improve treatment success with focus on rural children. https://www.panafrican-med-journal.com/content/article/27/25/pdf/25.pdf treatment outcomesdeterminantschildrendeveloping country |
| spellingShingle | Zemene Tigabu Kebede Belaynew Wasie Taye Yohannes Hailu Matebe Childhood tuberculosis: management and treatment outcomes among children in Northwest Ethiopia: a cross-sectional study The Pan African Medical Journal treatment outcomes determinants children developing country |
| title | Childhood tuberculosis: management and treatment outcomes among children in Northwest Ethiopia: a cross-sectional study |
| title_full | Childhood tuberculosis: management and treatment outcomes among children in Northwest Ethiopia: a cross-sectional study |
| title_fullStr | Childhood tuberculosis: management and treatment outcomes among children in Northwest Ethiopia: a cross-sectional study |
| title_full_unstemmed | Childhood tuberculosis: management and treatment outcomes among children in Northwest Ethiopia: a cross-sectional study |
| title_short | Childhood tuberculosis: management and treatment outcomes among children in Northwest Ethiopia: a cross-sectional study |
| title_sort | childhood tuberculosis management and treatment outcomes among children in northwest ethiopia a cross sectional study |
| topic | treatment outcomes determinants children developing country |
| url |
https://www.panafrican-med-journal.com/content/article/27/25/pdf/25.pdf
|
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