Impairment of cell division of Trypanosoma cruzi epimastigotes
The mechanisms that facilitate the adaptation of Trypanosoma cruzi to two distinct hosts, insect and vertebrate, are poorly understood, in part due to the limited ability to perform gene disruption studies by homologous recombination. This report describes a developmentally-defective phenotype that...
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2007-02-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000100019&lng=en&tlng=en |
| _version_ | 1827880279820206080 |
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| author | Michele A Zacks |
| author_facet | Michele A Zacks |
| author_sort | Michele A Zacks |
| collection | DOAJ |
| description | The mechanisms that facilitate the adaptation of Trypanosoma cruzi to two distinct hosts, insect and vertebrate, are poorly understood, in part due to the limited ability to perform gene disruption studies by homologous recombination. This report describes a developmentally-defective phenotype that resulted from integration of a drug marker adjacent to the GAPDH gene in T. cruzi. |
| first_indexed | 2024-03-12T18:19:26Z |
| format | Article |
| id | doaj.art-9eefffbd5af242af86463bda47868b3a |
| institution | Directory Open Access Journal |
| issn | 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T18:19:26Z |
| publishDate | 2007-02-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-9eefffbd5af242af86463bda47868b3a2023-08-02T08:59:59ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz1678-80602007-02-01102111111510.1590/S0074-02762007000100019S0074-02762007000100019Impairment of cell division of Trypanosoma cruzi epimastigotesMichele A Zacks0University of Texas Medical BranchThe mechanisms that facilitate the adaptation of Trypanosoma cruzi to two distinct hosts, insect and vertebrate, are poorly understood, in part due to the limited ability to perform gene disruption studies by homologous recombination. This report describes a developmentally-defective phenotype that resulted from integration of a drug marker adjacent to the GAPDH gene in T. cruzi.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000100019&lng=en&tlng=enTrypanosoma cruzilife cycledifferentiation |
| spellingShingle | Michele A Zacks Impairment of cell division of Trypanosoma cruzi epimastigotes Memorias do Instituto Oswaldo Cruz Trypanosoma cruzi life cycle differentiation |
| title | Impairment of cell division of Trypanosoma cruzi epimastigotes |
| title_full | Impairment of cell division of Trypanosoma cruzi epimastigotes |
| title_fullStr | Impairment of cell division of Trypanosoma cruzi epimastigotes |
| title_full_unstemmed | Impairment of cell division of Trypanosoma cruzi epimastigotes |
| title_short | Impairment of cell division of Trypanosoma cruzi epimastigotes |
| title_sort | impairment of cell division of trypanosoma cruzi epimastigotes |
| topic | Trypanosoma cruzi life cycle differentiation |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000100019&lng=en&tlng=en |
| work_keys_str_mv | AT micheleazacks impairmentofcelldivisionoftrypanosomacruziepimastigotes |