Antibiotic use in Departments of Internal Medicine of Lazio
Antimicrobial therapy is inappropriate in 9 to 64% of the patients hospitalized. We evaluated the antibiotic use in Internal Medicine wards of an Italian region (Lazio) by a prospective multicenter, observational study. One thousand and nine patients were evaluated. Patients under antimicrobial trea...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2017-11-01
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| Series: | Italian Journal of Medicine |
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| Online Access: | http://www.italjmed.org/index.php/ijm/article/view/814 |
| _version_ | 1797430270375231488 |
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| author | Dario Martolini Maurizia Galiè Anna Maria Santoro Danilo Monno Claudio Santini David Terracina on behalf of FADOI Lazio - Area of Infectious Diseases |
| author_facet | Dario Martolini Maurizia Galiè Anna Maria Santoro Danilo Monno Claudio Santini David Terracina on behalf of FADOI Lazio - Area of Infectious Diseases |
| author_sort | Dario Martolini |
| collection | DOAJ |
| description | Antimicrobial therapy is inappropriate in 9 to 64% of the patients hospitalized. We evaluated the antibiotic use in Internal Medicine wards of an Italian region (Lazio) by a prospective multicenter, observational study. One thousand and nine patients were evaluated. Patients under antimicrobial treatment (PUAT) were 588 (58.2%), patients without treatment (PWT) 421 (41.8%). Infections were classified as community acquired (47.8%), hospital acquired (10.3%) or healthcare-associated (11.4%); the remaining 30.5% of infections did not receive any epidemiological classification. Samples for microbiological examination were collected in 41.6% of PUAT. The antibiotic choice was empiric in 94.8% of the cases and protected penicillins were selected in 48% of the cases. The mean duration of treatment was 9.5±6 standard deviation (SD) days. Only 6% of the patients switched from intravenous to oral therapy. Age, length of hospital stay and mortality were higher for PUAT than for PWT (mean age: 75.9±15 SD vs 74.2±15 SD years, P<0.02; length of hospital stay: 13.7±10.4 SD vs 10±8.4 SD days, P<0.01; mortality: 15.9% vs 3.1%). Antibiotic stewardship needs to be implemented all over the hospitals of Lazio region. |
| first_indexed | 2024-03-09T09:26:14Z |
| format | Article |
| id | doaj.art-9ef24b8961214c30b9a44a42bd7a7304 |
| institution | Directory Open Access Journal |
| issn | 1877-9344 1877-9352 |
| language | English |
| last_indexed | 2024-03-09T09:26:14Z |
| publishDate | 2017-11-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Italian Journal of Medicine |
| spelling | doaj.art-9ef24b8961214c30b9a44a42bd7a73042023-12-02T06:03:35ZengPAGEPress PublicationsItalian Journal of Medicine1877-93441877-93522017-11-0111436437010.4081/itjm.2017.814650Antibiotic use in Departments of Internal Medicine of LazioDario Martolini0Maurizia Galiè1Anna Maria Santoro2Danilo Monno3Claudio Santini4David Terracina5on behalf of FADOI Lazio - Area of Infectious DiseasesDepartment of Internal Medicine, Madre Giuseppina Vannini Hospital, Figlie di San Camillo Institute, RomaDepartment of Internal Medicine, Madre Giuseppina Vannini Hospital, Figlie di San Camillo Institute, RomaDepartment of Internal Medicine, Sandro Pertini Hospital, RomaDepartment of Internal Medicine, Fatebenefratelli Hospital, Isola Tiberina, RomaDepartment of Internal Medicine, Madre Giuseppina Vannini Hospital, Figlie di San Camillo Institute, RomaDepartment of Internal Medicine, Sandro Pertini Hospital, RomaAntimicrobial therapy is inappropriate in 9 to 64% of the patients hospitalized. We evaluated the antibiotic use in Internal Medicine wards of an Italian region (Lazio) by a prospective multicenter, observational study. One thousand and nine patients were evaluated. Patients under antimicrobial treatment (PUAT) were 588 (58.2%), patients without treatment (PWT) 421 (41.8%). Infections were classified as community acquired (47.8%), hospital acquired (10.3%) or healthcare-associated (11.4%); the remaining 30.5% of infections did not receive any epidemiological classification. Samples for microbiological examination were collected in 41.6% of PUAT. The antibiotic choice was empiric in 94.8% of the cases and protected penicillins were selected in 48% of the cases. The mean duration of treatment was 9.5±6 standard deviation (SD) days. Only 6% of the patients switched from intravenous to oral therapy. Age, length of hospital stay and mortality were higher for PUAT than for PWT (mean age: 75.9±15 SD vs 74.2±15 SD years, P<0.02; length of hospital stay: 13.7±10.4 SD vs 10±8.4 SD days, P<0.01; mortality: 15.9% vs 3.1%). Antibiotic stewardship needs to be implemented all over the hospitals of Lazio region.http://www.italjmed.org/index.php/ijm/article/view/814Antibiotic consumptionantibiotic stewardshipinfectious diseases. |
| spellingShingle | Dario Martolini Maurizia Galiè Anna Maria Santoro Danilo Monno Claudio Santini David Terracina on behalf of FADOI Lazio - Area of Infectious Diseases Antibiotic use in Departments of Internal Medicine of Lazio Italian Journal of Medicine Antibiotic consumption antibiotic stewardship infectious diseases. |
| title | Antibiotic use in Departments of Internal Medicine of Lazio |
| title_full | Antibiotic use in Departments of Internal Medicine of Lazio |
| title_fullStr | Antibiotic use in Departments of Internal Medicine of Lazio |
| title_full_unstemmed | Antibiotic use in Departments of Internal Medicine of Lazio |
| title_short | Antibiotic use in Departments of Internal Medicine of Lazio |
| title_sort | antibiotic use in departments of internal medicine of lazio |
| topic | Antibiotic consumption antibiotic stewardship infectious diseases. |
| url | http://www.italjmed.org/index.php/ijm/article/view/814 |
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