BRG1 is a biomarker of hypertrophic cardiomyopathy in human heart specimens

Abstract Hypertrophic cardiomyopathy (HCM) is a genetic disease of the sarcomere that causes otherwise unexplained cardiac hypertrophy and is associated with sudden death. While previous studies showed the role of the epigenetic modifier Brg1 in mouse models of HCM, additional work is needed to iden...

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Bibliographic Details
Main Authors: Jacob C. Scherba, Marc K. Halushka, Nicholas D. Andersen, Joseph J. Maleszewski, Andrew P. Landstrom, Nenad Bursac, Carolyn Glass
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11829-x

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