Importance of Autophagy in Mediating Cellular Responses to Iron Overload in Cardiomyocytes

Importance of Autophagy in Mediating Cellular Responses to Iron Overload in Cardiomyocytes

Both iron overload and deficiency can promote development of cardiomyopathy. Advances in our knowledge from recent research have indicated numerous potential cellular mechanisms. Regulation of myocardial autophagy by iron is of particular interest and will be reviewed here. Autophagy is already well...

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Bibliographic Details
Main Authors: Eddie Tam, Chloe Reno, Khang Nguyen, Sungji Cho, Gary Sweeney
Format: Article
Language:English
Published: IMR Press 2022-05-01
Series:Reviews in Cardiovascular Medicine
Subjects:
iron overload
autophagy
adiponectin
oxidative stress
endoplasmic reticulum stress
mitochondria
ferroptosis
Online Access:https://www.imrpress.com/journal/RCM/23/5/10.31083/j.rcm2305167

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