Challenges in managing a multifactorial eosinophilic pneumonia: daptomycin vs strongyloidiasis case report
Abstract Background Eosinophilia is defined as a blood eosinophil count > 500/mcL with etiology usually an allergic reaction or parasitic infection which can lead to serious organ damage. Case presentation A patient being treated for hardware infection develops eosinophilia while on daptomycin in...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-11-01
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| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12879-022-07852-y |
| _version_ | 1811187019781505024 |
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| author | Lynda G. J. Eckhardt Jordan L. Kelley Dorothy Maes |
| author_facet | Lynda G. J. Eckhardt Jordan L. Kelley Dorothy Maes |
| author_sort | Lynda G. J. Eckhardt |
| collection | DOAJ |
| description | Abstract Background Eosinophilia is defined as a blood eosinophil count > 500/mcL with etiology usually an allergic reaction or parasitic infection which can lead to serious organ damage. Case presentation A patient being treated for hardware infection develops eosinophilia while on daptomycin in the setting of a positive strongyloides antibody. The patient was on chronic steroids prior to admission for epitheliopathy which complicated care. The daptomycin was discontinued, ivermectin initiated to treat strongyloidiasis, and high dose steroids initiated simultaneously. Eosinophilia resolved and patient discharged home after two months in the hospital. Conclusion Multifactorial eosinophilia poses question of steroid harm in the setting of parasitic infection. Patient was treated for both strongyloides and daptomycin induced eosinophilia with improvement and discharge from the hospital. |
| first_indexed | 2024-04-11T13:55:11Z |
| format | Article |
| id | doaj.art-9efd33416eb8447bb61bf5dbc101590c |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-04-11T13:55:11Z |
| publishDate | 2022-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-9efd33416eb8447bb61bf5dbc101590c2022-12-22T04:20:22ZengBMCBMC Infectious Diseases1471-23342022-11-012211510.1186/s12879-022-07852-yChallenges in managing a multifactorial eosinophilic pneumonia: daptomycin vs strongyloidiasis case reportLynda G. J. Eckhardt0Jordan L. Kelley1Dorothy Maes2Department of Pharmacy Services, University of Kentucky HealthCare Good Samaritan HospitalDepartment of Pharmacy Services, University of Kentucky HealthCare Good Samaritan HospitalDepartment of Pulmonary, Critical Care and Sleep Medicine, University of Kentucky Medical CenterAbstract Background Eosinophilia is defined as a blood eosinophil count > 500/mcL with etiology usually an allergic reaction or parasitic infection which can lead to serious organ damage. Case presentation A patient being treated for hardware infection develops eosinophilia while on daptomycin in the setting of a positive strongyloides antibody. The patient was on chronic steroids prior to admission for epitheliopathy which complicated care. The daptomycin was discontinued, ivermectin initiated to treat strongyloidiasis, and high dose steroids initiated simultaneously. Eosinophilia resolved and patient discharged home after two months in the hospital. Conclusion Multifactorial eosinophilia poses question of steroid harm in the setting of parasitic infection. Patient was treated for both strongyloides and daptomycin induced eosinophilia with improvement and discharge from the hospital.https://doi.org/10.1186/s12879-022-07852-yEosinophiliaDaptomycinStrongyloidesCorticosteroidsPulmonary |
| spellingShingle | Lynda G. J. Eckhardt Jordan L. Kelley Dorothy Maes Challenges in managing a multifactorial eosinophilic pneumonia: daptomycin vs strongyloidiasis case report BMC Infectious Diseases Eosinophilia Daptomycin Strongyloides Corticosteroids Pulmonary |
| title | Challenges in managing a multifactorial eosinophilic pneumonia: daptomycin vs strongyloidiasis case report |
| title_full | Challenges in managing a multifactorial eosinophilic pneumonia: daptomycin vs strongyloidiasis case report |
| title_fullStr | Challenges in managing a multifactorial eosinophilic pneumonia: daptomycin vs strongyloidiasis case report |
| title_full_unstemmed | Challenges in managing a multifactorial eosinophilic pneumonia: daptomycin vs strongyloidiasis case report |
| title_short | Challenges in managing a multifactorial eosinophilic pneumonia: daptomycin vs strongyloidiasis case report |
| title_sort | challenges in managing a multifactorial eosinophilic pneumonia daptomycin vs strongyloidiasis case report |
| topic | Eosinophilia Daptomycin Strongyloides Corticosteroids Pulmonary |
| url | https://doi.org/10.1186/s12879-022-07852-y |
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