Mutation landscape in Chinese nodal diffuse large B-cell lymphoma by targeted next generation sequencing and their relationship with clinicopathological characteristics

Mutation landscape in Chinese nodal diffuse large B-cell lymphoma by targeted next generation sequencing and their relationship with clinicopathological characteristics

Abstract Background Diffuse large B-cell lymphoma (DLBCL), an aggressive and heterogenic malignant entity, is still a challenging clinical problem, since around one-third of patients are not cured with primary treatment. Next-generation sequencing (NGS) technologies have revealed common genetic muta...

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Bibliographic Details
Main Authors: Bing Cao, Chenbo Sun, Rui Bi, Zebing Liu, Yijun Jia, Wenli Cui, Menghong Sun, Baohua Yu, Xiaoqiu Li, Xiaoyan Zhou
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Medical Genomics
Subjects:
Diffuse large B-cell lymphoma
Targeted sequencing
Next-generation sequencing
Mutation
Genetic subtype
Online Access:https://doi.org/10.1186/s12920-024-01866-y

Internet

https://doi.org/10.1186/s12920-024-01866-y

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