Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain Study
The aim was to assess the effect of adherence to the Mediterranean Diet, measured with five different indexes, on the risk of gastric cancer. Data come from the multicase-control study MCC—Spain, which included 354 gastric cancer cases and 3040 controls with data on diet. We used five indexes to eva...
| Main Authors: | , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-10-01
|
| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/13/21/5281 |
| _version_ | 1797410972935127040 |
|---|---|
| author | Laura Álvarez-Álvarez Facundo Vitelli-Storelli María Rubín-García Nuria Aragonés Eva Ardanaz Gemma Castaño-Vinyals Mireia Obón-Santacana Trinidad Dierssen-Sotos Dolores Salas-Trejo Adonina Tardón José Juan Jiménez Moleón Juan Alguacil María Dolores Chirlaque Beatriz Pérez-Gómez Marina Pollán Manolis Kogevinas Vicente Martín |
| author_facet | Laura Álvarez-Álvarez Facundo Vitelli-Storelli María Rubín-García Nuria Aragonés Eva Ardanaz Gemma Castaño-Vinyals Mireia Obón-Santacana Trinidad Dierssen-Sotos Dolores Salas-Trejo Adonina Tardón José Juan Jiménez Moleón Juan Alguacil María Dolores Chirlaque Beatriz Pérez-Gómez Marina Pollán Manolis Kogevinas Vicente Martín |
| author_sort | Laura Álvarez-Álvarez |
| collection | DOAJ |
| description | The aim was to assess the effect of adherence to the Mediterranean Diet, measured with five different indexes, on the risk of gastric cancer. Data come from the multicase-control study MCC—Spain, which included 354 gastric cancer cases and 3040 controls with data on diet. We used five indexes to evaluate adherence to the Mediterranean diet and assess the association between each pattern with the risk of gastric cancer, using multivariate logistic regression. The analyses were performed for the whole set of gastric cancer cases, by anatomical location (cardia and non-cardia) and by histological type (intestinal and diffuse). According to the used index, a high adherence protects one from gastric cancer (between 48% (aOR = 0.52; CI 95% = 0.28–0.94) and 75% (aOR = 0.25; CI 95% = 0.12–0.52)), from non-cardia (between 48% (aOR = 0.52; CI 95% = 0.36–0.75) and 65% (aOR = 0.35; CI 95% = 0.23–0.52)), and from the intestinal type (between 41% (aOR = 0.59; CI 95% = 0.36–0.95) and 72% (aOR = 0.28; CI 95% = 0.16–0.50)), but not from the diffuse type. In conclusion, high adherence to a Mediterranean diet pattern is a protective factor for the risk of gastric cancer, with greater adherence leading to greater protection. |
| first_indexed | 2024-03-09T04:38:16Z |
| format | Article |
| id | doaj.art-9f0869cb67e347e4add98d121e5c11b9 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-09T04:38:16Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-9f0869cb67e347e4add98d121e5c11b92023-12-03T13:25:03ZengMDPI AGCancers2072-66942021-10-011321528110.3390/cancers13215281Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain StudyLaura Álvarez-Álvarez0Facundo Vitelli-Storelli1María Rubín-García2Nuria Aragonés3Eva Ardanaz4Gemma Castaño-Vinyals5Mireia Obón-Santacana6Trinidad Dierssen-Sotos7Dolores Salas-Trejo8Adonina Tardón9José Juan Jiménez Moleón10Juan Alguacil11María Dolores Chirlaque12Beatriz Pérez-Gómez13Marina Pollán14Manolis Kogevinas15Vicente Martín16Group of Investigation in Interactions Gene-Environment and Health (GIIGAS), Institute of Biomedicine (IBIOMED), University of León, 24071 León, SpainGroup of Investigation in Interactions Gene-Environment and Health (GIIGAS), Institute of Biomedicine (IBIOMED), University of León, 24071 León, SpainGroup of Investigation in Interactions Gene-Environment and Health (GIIGAS), Institute of Biomedicine (IBIOMED), University of León, 24071 León, SpainConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, SpainConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, SpainConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, SpainOncology Data Analytics Program (ODAP), Catalan Institute of Oncology (ICO), L’Hospitalet Del Llobregat, 08908 Barcelona, SpainConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, SpainConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, SpainConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, SpainConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, SpainConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, SpainConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, SpainConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, SpainConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, SpainConsortium for Biomedical Research in Epidemiology & Public Health, CIBERESP, 28029 Madrid, SpainGroup of Investigation in Interactions Gene-Environment and Health (GIIGAS), Institute of Biomedicine (IBIOMED), University of León, 24071 León, SpainThe aim was to assess the effect of adherence to the Mediterranean Diet, measured with five different indexes, on the risk of gastric cancer. Data come from the multicase-control study MCC—Spain, which included 354 gastric cancer cases and 3040 controls with data on diet. We used five indexes to evaluate adherence to the Mediterranean diet and assess the association between each pattern with the risk of gastric cancer, using multivariate logistic regression. The analyses were performed for the whole set of gastric cancer cases, by anatomical location (cardia and non-cardia) and by histological type (intestinal and diffuse). According to the used index, a high adherence protects one from gastric cancer (between 48% (aOR = 0.52; CI 95% = 0.28–0.94) and 75% (aOR = 0.25; CI 95% = 0.12–0.52)), from non-cardia (between 48% (aOR = 0.52; CI 95% = 0.36–0.75) and 65% (aOR = 0.35; CI 95% = 0.23–0.52)), and from the intestinal type (between 41% (aOR = 0.59; CI 95% = 0.36–0.95) and 72% (aOR = 0.28; CI 95% = 0.16–0.50)), but not from the diffuse type. In conclusion, high adherence to a Mediterranean diet pattern is a protective factor for the risk of gastric cancer, with greater adherence leading to greater protection.https://www.mdpi.com/2072-6694/13/21/5281dietMediterraneanfeeding behaviourstomach neoplasms |
| spellingShingle | Laura Álvarez-Álvarez Facundo Vitelli-Storelli María Rubín-García Nuria Aragonés Eva Ardanaz Gemma Castaño-Vinyals Mireia Obón-Santacana Trinidad Dierssen-Sotos Dolores Salas-Trejo Adonina Tardón José Juan Jiménez Moleón Juan Alguacil María Dolores Chirlaque Beatriz Pérez-Gómez Marina Pollán Manolis Kogevinas Vicente Martín Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain Study Cancers diet Mediterranean feeding behaviour stomach neoplasms |
| title | Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain Study |
| title_full | Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain Study |
| title_fullStr | Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain Study |
| title_full_unstemmed | Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain Study |
| title_short | Relationship between the Risk of Gastric Cancer and Adherence to the Mediterranean Diet According to Different Estimators. MCC—Spain Study |
| title_sort | relationship between the risk of gastric cancer and adherence to the mediterranean diet according to different estimators mcc spain study |
| topic | diet Mediterranean feeding behaviour stomach neoplasms |
| url | https://www.mdpi.com/2072-6694/13/21/5281 |
| work_keys_str_mv | AT lauraalvarezalvarez relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy AT facundovitellistorelli relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy AT mariarubingarcia relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy AT nuriaaragones relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy AT evaardanaz relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy AT gemmacastanovinyals relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy AT mireiaobonsantacana relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy AT trinidaddierssensotos relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy AT doloressalastrejo relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy AT adoninatardon relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy AT josejuanjimenezmoleon relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy AT juanalguacil relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy AT mariadoloreschirlaque relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy AT beatrizperezgomez relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy AT marinapollan relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy AT manoliskogevinas relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy AT vicentemartin relationshipbetweentheriskofgastriccancerandadherencetothemediterraneandietaccordingtodifferentestimatorsmccspainstudy |