Comparison of chicken immune responses after inoculation with H5 avian influenza virus-like particles produced by insect cells or pupae

Novel clade 2.3.4.4 H5 highly pathogenic avian influenza virus (HPAIV) outbreaks have occurred since early 2015 in Taiwan and impacted the island economically, like they have many countries. This research investigates the immunogenicity of two HPAIV-like particles to assess their promise as vaccine...

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Main Authors: Huang Dean, Chao Yu-Chan, Lv Zhengbing, Jan Jia-Tsrong, Yang Yu-Chih, Hsiao Pei-Wen, Wu Chia-Ying, Liao Chiu-Hsun, Wu Tzu-Hsien, Wang Lih-Chiann
Format: Article
Language:English
Published: Sciendo 2021-05-01
Series:Journal of Veterinary Research
Subjects:
Online Access:https://doi.org/10.2478/jvetres-2021-0026
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author Huang Dean
Chao Yu-Chan
Lv Zhengbing
Jan Jia-Tsrong
Yang Yu-Chih
Hsiao Pei-Wen
Wu Chia-Ying
Liao Chiu-Hsun
Wu Tzu-Hsien
Wang Lih-Chiann
author_facet Huang Dean
Chao Yu-Chan
Lv Zhengbing
Jan Jia-Tsrong
Yang Yu-Chih
Hsiao Pei-Wen
Wu Chia-Ying
Liao Chiu-Hsun
Wu Tzu-Hsien
Wang Lih-Chiann
author_sort Huang Dean
collection DOAJ
description Novel clade 2.3.4.4 H5 highly pathogenic avian influenza virus (HPAIV) outbreaks have occurred since early 2015 in Taiwan and impacted the island economically, like they have many countries. This research investigates the immunogenicity of two HPAIV-like particles to assess their promise as vaccine candidates.
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spelling doaj.art-9f0a20b9fc3045e8b86dafaded7532502022-12-21T19:18:40ZengSciendoJournal of Veterinary Research2450-86082021-05-0165213914510.2478/jvetres-2021-0026Comparison of chicken immune responses after inoculation with H5 avian influenza virus-like particles produced by insect cells or pupaeHuang Dean0Chao Yu-Chan1Lv Zhengbing2Jan Jia-Tsrong3Yang Yu-Chih4Hsiao Pei-Wen5Wu Chia-Ying6Liao Chiu-Hsun7Wu Tzu-Hsien8Wang Lih-Chiann9School of Veterinary Medicine, National Taiwan University, Taipei10617, TaiwanAcademia Sinica, Taipei11529, TaiwanCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou310018, ChinaAcademia Sinica, Taipei11529, TaiwanAcademia Sinica, Taipei11529, TaiwanAcademia Sinica, Taipei11529, TaiwanAcademia Sinica, Taipei11529, TaiwanMiaoli District Agricultural Research and Extension Station, Council of Agriculture, Miaoli36346, TaiwanMiaoli District Agricultural Research and Extension Station, Council of Agriculture, Miaoli36346, TaiwanSchool of Veterinary Medicine, National Taiwan University, Taipei10617, TaiwanNovel clade 2.3.4.4 H5 highly pathogenic avian influenza virus (HPAIV) outbreaks have occurred since early 2015 in Taiwan and impacted the island economically, like they have many countries. This research investigates the immunogenicity of two HPAIV-like particles to assess their promise as vaccine candidates.https://doi.org/10.2478/jvetres-2021-0026avian influenza virusclade 2.3.4.4silkworm pupavaccinevirus-like particle
spellingShingle Huang Dean
Chao Yu-Chan
Lv Zhengbing
Jan Jia-Tsrong
Yang Yu-Chih
Hsiao Pei-Wen
Wu Chia-Ying
Liao Chiu-Hsun
Wu Tzu-Hsien
Wang Lih-Chiann
Comparison of chicken immune responses after inoculation with H5 avian influenza virus-like particles produced by insect cells or pupae
Journal of Veterinary Research
avian influenza virus
clade 2.3.4.4
silkworm pupa
vaccine
virus-like particle
title Comparison of chicken immune responses after inoculation with H5 avian influenza virus-like particles produced by insect cells or pupae
title_full Comparison of chicken immune responses after inoculation with H5 avian influenza virus-like particles produced by insect cells or pupae
title_fullStr Comparison of chicken immune responses after inoculation with H5 avian influenza virus-like particles produced by insect cells or pupae
title_full_unstemmed Comparison of chicken immune responses after inoculation with H5 avian influenza virus-like particles produced by insect cells or pupae
title_short Comparison of chicken immune responses after inoculation with H5 avian influenza virus-like particles produced by insect cells or pupae
title_sort comparison of chicken immune responses after inoculation with h5 avian influenza virus like particles produced by insect cells or pupae
topic avian influenza virus
clade 2.3.4.4
silkworm pupa
vaccine
virus-like particle
url https://doi.org/10.2478/jvetres-2021-0026
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