The Impact of Glycerol on an Affibody Conformation and Its Correlation to Chemical Degradation

The addition of glycerol to protein solutions is often used to hinder the aggregation and denaturation of proteins. However, it is not a generalised practice against chemical degradation reactions. The chemical degradation of proteins, such as deamidation and isomerisation, is an important deteriora...

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Bibliographic Details
Main Authors: Ingrid Ramm, Adrian Sanchez-Fernandez, Jaeyeong Choi, Christian Lang, Jonas Fransson, Herje Schagerlöf, Marie Wahlgren, Lars Nilsson
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/13/11/1853