Traditional uses and pharmacological properties of Clerodendrum phytochemicals
Clerodendrum is a genus of ca. 500 species in the family Lamiaceae and widely distributed throughout the whole world. Up to now, many species of this genus have been described in various indigenous systems of medicine and are used in preparation of folklore medicines for the treatment of various lif...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018-01-01
|
| Series: | Journal of Traditional and Complementary Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S222541101730041X |
| _version_ | 1818140778536370176 |
|---|---|
| author | Jin-Hui Wang Fei Luan Xiang-Dong He Yong Wang Mao-Xing Li |
| author_facet | Jin-Hui Wang Fei Luan Xiang-Dong He Yong Wang Mao-Xing Li |
| author_sort | Jin-Hui Wang |
| collection | DOAJ |
| description | Clerodendrum is a genus of ca. 500 species in the family Lamiaceae and widely distributed throughout the whole world. Up to now, many species of this genus have been described in various indigenous systems of medicine and are used in preparation of folklore medicines for the treatment of various life-threatening diseases, and more than eleven species of the Clerodendrum genus have been very well studied for their chemical constituents and biological activities, and 283 compounds, including monoterpene and its derivatives, sesquiterpene, diterpenoids, triterpenoids, flavonoid and flavonoid glycosides, phenylethanoid glycosides, steroids and steroid glycosides, cyclohexylethanoids, anthraquinones, cyanogenic glycosides, and others have been isolated and identified. Pharmacological studies have shown that these compounds and extracts from the Clerodendrum genus have extensive activities, such as anti-inflammatory and anti-nociceptive, anti-oxidant, anti-hypertensive, anticancer, antimicrobial, anti-diarrheal, hepatoprotective, hypoglycemic and hypolipidemic, memory enhancing and neuroprotective, and other activities. In this review, we attempt to highlight over phytochemical progress and list the phytoconstituents isolated from the genus Clerodendrum reported so far. The biological activities of this genus are also covered. |
| first_indexed | 2024-12-11T10:49:24Z |
| format | Article |
| id | doaj.art-9f1e60d03cbd40ba8ad215a2dde4b544 |
| institution | Directory Open Access Journal |
| issn | 2225-4110 |
| language | English |
| last_indexed | 2024-12-11T10:49:24Z |
| publishDate | 2018-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Traditional and Complementary Medicine |
| spelling | doaj.art-9f1e60d03cbd40ba8ad215a2dde4b5442022-12-22T01:10:22ZengElsevierJournal of Traditional and Complementary Medicine2225-41102018-01-0181243810.1016/j.jtcme.2017.04.001Traditional uses and pharmacological properties of Clerodendrum phytochemicalsJin-Hui Wang0Fei Luan1Xiang-Dong He2Yong Wang3Mao-Xing Li4Department of Pharmacy, Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730000, Gansu, ChinaDepartment of Pharmacy, Xi'an Weiyang District Hospital of Chinese Medicine, Xi'an 710015, Shanxi, ChinaDepartment of Clinical Laboratory, Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730000, Gansu, ChinaDepartment of Pharmacy, Xi'an Weiyang District Hospital of Chinese Medicine, Xi'an 710015, Shanxi, ChinaDepartment of Pharmacy, Lanzhou General Hospital of PLA, Key Laboratory of the Prevention and Treatment for Injury in Plateau of PLA, Lanzhou 730050, Gansu, ChinaClerodendrum is a genus of ca. 500 species in the family Lamiaceae and widely distributed throughout the whole world. Up to now, many species of this genus have been described in various indigenous systems of medicine and are used in preparation of folklore medicines for the treatment of various life-threatening diseases, and more than eleven species of the Clerodendrum genus have been very well studied for their chemical constituents and biological activities, and 283 compounds, including monoterpene and its derivatives, sesquiterpene, diterpenoids, triterpenoids, flavonoid and flavonoid glycosides, phenylethanoid glycosides, steroids and steroid glycosides, cyclohexylethanoids, anthraquinones, cyanogenic glycosides, and others have been isolated and identified. Pharmacological studies have shown that these compounds and extracts from the Clerodendrum genus have extensive activities, such as anti-inflammatory and anti-nociceptive, anti-oxidant, anti-hypertensive, anticancer, antimicrobial, anti-diarrheal, hepatoprotective, hypoglycemic and hypolipidemic, memory enhancing and neuroprotective, and other activities. In this review, we attempt to highlight over phytochemical progress and list the phytoconstituents isolated from the genus Clerodendrum reported so far. The biological activities of this genus are also covered.http://www.sciencedirect.com/science/article/pii/S222541101730041XClerodendrumDiterpenoidsTriterpenoidsFlavonoidsPhenylethanoid glycosidesBiological activity |
| spellingShingle | Jin-Hui Wang Fei Luan Xiang-Dong He Yong Wang Mao-Xing Li Traditional uses and pharmacological properties of Clerodendrum phytochemicals Journal of Traditional and Complementary Medicine Clerodendrum Diterpenoids Triterpenoids Flavonoids Phenylethanoid glycosides Biological activity |
| title | Traditional uses and pharmacological properties of Clerodendrum phytochemicals |
| title_full | Traditional uses and pharmacological properties of Clerodendrum phytochemicals |
| title_fullStr | Traditional uses and pharmacological properties of Clerodendrum phytochemicals |
| title_full_unstemmed | Traditional uses and pharmacological properties of Clerodendrum phytochemicals |
| title_short | Traditional uses and pharmacological properties of Clerodendrum phytochemicals |
| title_sort | traditional uses and pharmacological properties of clerodendrum phytochemicals |
| topic | Clerodendrum Diterpenoids Triterpenoids Flavonoids Phenylethanoid glycosides Biological activity |
| url | http://www.sciencedirect.com/science/article/pii/S222541101730041X |
| work_keys_str_mv | AT jinhuiwang traditionalusesandpharmacologicalpropertiesofclerodendrumphytochemicals AT feiluan traditionalusesandpharmacologicalpropertiesofclerodendrumphytochemicals AT xiangdonghe traditionalusesandpharmacologicalpropertiesofclerodendrumphytochemicals AT yongwang traditionalusesandpharmacologicalpropertiesofclerodendrumphytochemicals AT maoxingli traditionalusesandpharmacologicalpropertiesofclerodendrumphytochemicals |