Significance of peak oxygen pulse in patients with chronic obstructive pulmonary disease
Abstract Background Patients with chronic obstructive pulmonary disease (COPD) are more likely to develop cardiovascular comorbidities, such as pulmonary hypertension or heart failure. COPD patients are frequently adversely affected by compromised cardiovascular function. Oxygen pulse (O2P) serves a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2023-07-01
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| Series: | The Egyptian Journal of Bronchology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43168-023-00205-6 |
| _version_ | 1797784781778321408 |
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| author | Mai Hassan Mohamed Mostafa Mahmoud Shahin Mona Said El Hoshy Heba Said Gharraf |
| author_facet | Mai Hassan Mohamed Mostafa Mahmoud Shahin Mona Said El Hoshy Heba Said Gharraf |
| author_sort | Mai Hassan Mohamed |
| collection | DOAJ |
| description | Abstract Background Patients with chronic obstructive pulmonary disease (COPD) are more likely to develop cardiovascular comorbidities, such as pulmonary hypertension or heart failure. COPD patients are frequently adversely affected by compromised cardiovascular function. Oxygen pulse (O2P) serves as a proxy for stroke volume. However, studies concerning O2P, health-related quality of life (HRQL), and exercise capacity in COPD patients are lacking. Our objective was to verify the association between O2P, exercise capacity, and severe COPD exacerbation. Materials and methods Fifty COPD patients were evaluated using spirometry, echocardiography, and a cardiopulmonary exercise test (CPET) for this study. Hospitalizations and emergency department visits due to COPD, as well as cardiovascular co-morbidities, were tracked. Patients with normal peak O2P and those with impaired peak O2P were compared for these measures. Peak oxygen consumption (O2P) was correlated with cardiopulmonary exercise testing (CPET) and lung function by simple linear regression. Results Higher exercise capacity (peak oxygen uptake and work rate) and fewer hospitalizations due to COPD were observed in patients with normal peak O2P. Forced expiratory volume in one second (FEV1) was found to have a statistically significant correlation with arterial oxygen pressure (O2P) in a linear regression model. Conclusion Hospitalization due to COPD and exercise ability are both significantly affected by peak O2P. Peak O2P is strongly correlated with FEV1. The severity of COPD can be measured in part by the patient's peak O2P. |
| first_indexed | 2024-03-13T00:44:46Z |
| format | Article |
| id | doaj.art-9f1e9fb0d93341db9eebc9c3c7c06507 |
| institution | Directory Open Access Journal |
| issn | 2314-8551 |
| language | English |
| last_indexed | 2024-03-13T00:44:46Z |
| publishDate | 2023-07-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Bronchology |
| spelling | doaj.art-9f1e9fb0d93341db9eebc9c3c7c065072023-07-09T11:08:23ZengSpringerOpenThe Egyptian Journal of Bronchology2314-85512023-07-0117111010.1186/s43168-023-00205-6Significance of peak oxygen pulse in patients with chronic obstructive pulmonary diseaseMai Hassan Mohamed0Mostafa Mahmoud Shahin1Mona Said El Hoshy2Heba Said Gharraf3Department of Chest Diseases, Faculty of Medicine, Alexandria UniversityDepartment of Chest Diseases, Faculty of Medicine, Alexandria UniversityDepartment of Chest Diseases, Faculty of Medicine, Alexandria UniversityDepartment of Chest Diseases, Faculty of Medicine, Alexandria UniversityAbstract Background Patients with chronic obstructive pulmonary disease (COPD) are more likely to develop cardiovascular comorbidities, such as pulmonary hypertension or heart failure. COPD patients are frequently adversely affected by compromised cardiovascular function. Oxygen pulse (O2P) serves as a proxy for stroke volume. However, studies concerning O2P, health-related quality of life (HRQL), and exercise capacity in COPD patients are lacking. Our objective was to verify the association between O2P, exercise capacity, and severe COPD exacerbation. Materials and methods Fifty COPD patients were evaluated using spirometry, echocardiography, and a cardiopulmonary exercise test (CPET) for this study. Hospitalizations and emergency department visits due to COPD, as well as cardiovascular co-morbidities, were tracked. Patients with normal peak O2P and those with impaired peak O2P were compared for these measures. Peak oxygen consumption (O2P) was correlated with cardiopulmonary exercise testing (CPET) and lung function by simple linear regression. Results Higher exercise capacity (peak oxygen uptake and work rate) and fewer hospitalizations due to COPD were observed in patients with normal peak O2P. Forced expiratory volume in one second (FEV1) was found to have a statistically significant correlation with arterial oxygen pressure (O2P) in a linear regression model. Conclusion Hospitalization due to COPD and exercise ability are both significantly affected by peak O2P. Peak O2P is strongly correlated with FEV1. The severity of COPD can be measured in part by the patient's peak O2P.https://doi.org/10.1186/s43168-023-00205-6Cardiopulmonary exercise (CPET)Peak oxygen pulseChronic obstructive pulmonary disease (COPD) |
| spellingShingle | Mai Hassan Mohamed Mostafa Mahmoud Shahin Mona Said El Hoshy Heba Said Gharraf Significance of peak oxygen pulse in patients with chronic obstructive pulmonary disease The Egyptian Journal of Bronchology Cardiopulmonary exercise (CPET) Peak oxygen pulse Chronic obstructive pulmonary disease (COPD) |
| title | Significance of peak oxygen pulse in patients with chronic obstructive pulmonary disease |
| title_full | Significance of peak oxygen pulse in patients with chronic obstructive pulmonary disease |
| title_fullStr | Significance of peak oxygen pulse in patients with chronic obstructive pulmonary disease |
| title_full_unstemmed | Significance of peak oxygen pulse in patients with chronic obstructive pulmonary disease |
| title_short | Significance of peak oxygen pulse in patients with chronic obstructive pulmonary disease |
| title_sort | significance of peak oxygen pulse in patients with chronic obstructive pulmonary disease |
| topic | Cardiopulmonary exercise (CPET) Peak oxygen pulse Chronic obstructive pulmonary disease (COPD) |
| url | https://doi.org/10.1186/s43168-023-00205-6 |
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