Recent technical advances in radiofrequency ablations for hepatocellular carcinoma
Radiofrequency ablation (RFA) has regarded as a curative treatment method for early stage hepatocellular carcinoma (HCC), providing comparable overall survival to surgical resection. However, lack of ideal guiding modality for RFA procedure and higher rate of local tumor progression (LTP) after trea...
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| Format: | Article |
| Language: | English |
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Society of Gastrointestinal Intervention
2021-10-01
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| Series: | International Journal of Gastrointestinal Intervention |
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| Online Access: | http://journaleditor.inforang.com/journal/view.html?doi=10.18528/ijgii210050 |
| _version_ | 1818690513150148608 |
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| author | Dong Ho Lee |
| author_facet | Dong Ho Lee |
| author_sort | Dong Ho Lee |
| collection | DOAJ |
| description | Radiofrequency ablation (RFA) has regarded as a curative treatment method for early stage hepatocellular carcinoma (HCC), providing comparable overall survival to surgical resection. However, lack of ideal guiding modality for RFA procedure and higher rate of local tumor progression (LTP) after treatment than surgical resection have been important limitations. To overcome the current limitations of RFA, the fusion imaging between real-time ultrasound and reference computed tomography/magnetic resonance images has been introduced. The fusion imaging could improve the feasibility of RFA for HCC by helping the accurate identification of target HCC, especially for invisible small HCC. In addition, RFA using multiple electrodes with multi-channel generator and various energy delivery modes could improve the therapeutic efficacy, by creating larger ablation volume than RFA using a single electrode. RFA using multiple electrodes can allow no touch ablation technique, which might have a potential to reduce LTP. In this review, these recently introduced ablation techniques will be discussed with the results of both animal and clinical studies. |
| first_indexed | 2024-12-17T12:27:11Z |
| format | Article |
| id | doaj.art-9f1ecc9f87da45229d0b7ccb1940b039 |
| institution | Directory Open Access Journal |
| issn | 2636-0004 |
| language | English |
| last_indexed | 2024-12-17T12:27:11Z |
| publishDate | 2021-10-01 |
| publisher | Society of Gastrointestinal Intervention |
| record_format | Article |
| series | International Journal of Gastrointestinal Intervention |
| spelling | doaj.art-9f1ecc9f87da45229d0b7ccb1940b0392022-12-21T21:48:43ZengSociety of Gastrointestinal InterventionInternational Journal of Gastrointestinal Intervention2636-00042021-10-0110416917410.18528/ijgii210050ijgii210050Recent technical advances in radiofrequency ablations for hepatocellular carcinomaDong Ho Lee0Department of Radiology, Seoul National University Hospital, Seoul, KoreaRadiofrequency ablation (RFA) has regarded as a curative treatment method for early stage hepatocellular carcinoma (HCC), providing comparable overall survival to surgical resection. However, lack of ideal guiding modality for RFA procedure and higher rate of local tumor progression (LTP) after treatment than surgical resection have been important limitations. To overcome the current limitations of RFA, the fusion imaging between real-time ultrasound and reference computed tomography/magnetic resonance images has been introduced. The fusion imaging could improve the feasibility of RFA for HCC by helping the accurate identification of target HCC, especially for invisible small HCC. In addition, RFA using multiple electrodes with multi-channel generator and various energy delivery modes could improve the therapeutic efficacy, by creating larger ablation volume than RFA using a single electrode. RFA using multiple electrodes can allow no touch ablation technique, which might have a potential to reduce LTP. In this review, these recently introduced ablation techniques will be discussed with the results of both animal and clinical studies.http://journaleditor.inforang.com/journal/view.html?doi=10.18528/ijgii210050hepatocellular carcinoma; multimodal imaging; radiofrequency ablation |
| spellingShingle | Dong Ho Lee Recent technical advances in radiofrequency ablations for hepatocellular carcinoma International Journal of Gastrointestinal Intervention hepatocellular carcinoma; multimodal imaging; radiofrequency ablation |
| title | Recent technical advances in radiofrequency ablations for hepatocellular carcinoma |
| title_full | Recent technical advances in radiofrequency ablations for hepatocellular carcinoma |
| title_fullStr | Recent technical advances in radiofrequency ablations for hepatocellular carcinoma |
| title_full_unstemmed | Recent technical advances in radiofrequency ablations for hepatocellular carcinoma |
| title_short | Recent technical advances in radiofrequency ablations for hepatocellular carcinoma |
| title_sort | recent technical advances in radiofrequency ablations for hepatocellular carcinoma |
| topic | hepatocellular carcinoma; multimodal imaging; radiofrequency ablation |
| url | http://journaleditor.inforang.com/journal/view.html?doi=10.18528/ijgii210050 |
| work_keys_str_mv | AT dongholee recenttechnicaladvancesinradiofrequencyablationsforhepatocellularcarcinoma |