Association between weight-adjusted-waist index and gallstones: an analysis of the National Health and Nutrition Examination Survey
Abstract Background The weight-adjusted-waist index (WWI) is a novel obesity index, and gallstones are associated with obesity. This study aimed to investigate the possible relationship between WWI and gallstones. Methods The datasets from the National Health and Nutrition Examination Survey (NHANES...
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | BMC Gastroenterology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12876-024-03127-9 |
| _version_ | 1827377274188464128 |
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| author | Si-Hua Wen Xin Tang Tao Tang Zheng-Rong Ye |
| author_facet | Si-Hua Wen Xin Tang Tao Tang Zheng-Rong Ye |
| author_sort | Si-Hua Wen |
| collection | DOAJ |
| description | Abstract Background The weight-adjusted-waist index (WWI) is a novel obesity index, and gallstones are associated with obesity. This study aimed to investigate the possible relationship between WWI and gallstones. Methods The datasets from the National Health and Nutrition Examination Survey (NHANES) 2017–2020 were used in a cross-sectional investigation. Multivariate linear regression models were used to examine the linear connection between WWI and gallstones incidence. Fitted smoothing curves and threshold effect analysis were used to describe the nonlinear relationship. Results The study comprised 8004 participants over the age of 20, including 833 reported with gallstones. Participants in the higher WWI tertile tended to have a higher gallstones prevalence. In the final adjusted model, a positive association between WWI and gallstones prevalence was observed (OR = 1.34, 95% CI: 1.20‒1.49). Participants in the highest WWI tertile had a significantly 71% higher risk of gallstones than those in the lowest WWI tertile (OR = 1.71, 95% CI: 1.35‒2.17). A nonlinear correlation was found between the WWI and gallstones prevalence, with an inflection point of 12.7. Conclusions Our study found that higher WWI levels connected with increased prevalence of gallstones. However, more prospective studies are needed to validate our findings. |
| first_indexed | 2024-03-08T12:37:40Z |
| format | Article |
| id | doaj.art-9f238c5dad964cb380e41ab4eef43a81 |
| institution | Directory Open Access Journal |
| issn | 1471-230X |
| language | English |
| last_indexed | 2024-03-08T12:37:40Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Gastroenterology |
| spelling | doaj.art-9f238c5dad964cb380e41ab4eef43a812024-01-21T12:23:47ZengBMCBMC Gastroenterology1471-230X2024-01-0124111110.1186/s12876-024-03127-9Association between weight-adjusted-waist index and gallstones: an analysis of the National Health and Nutrition Examination SurveySi-Hua Wen0Xin Tang1Tao Tang2Zheng-Rong Ye3Department of Abdominal Surgery, The Third People’s Hospital of YongzhouDepartment of Hepatobiliary Surgery, The Central Hospital of YongzhouDepartment of Abdominal Surgery, The Third People’s Hospital of YongzhouDepartment of Endocrinology, The Third People’s Hospital of YongzhouAbstract Background The weight-adjusted-waist index (WWI) is a novel obesity index, and gallstones are associated with obesity. This study aimed to investigate the possible relationship between WWI and gallstones. Methods The datasets from the National Health and Nutrition Examination Survey (NHANES) 2017–2020 were used in a cross-sectional investigation. Multivariate linear regression models were used to examine the linear connection between WWI and gallstones incidence. Fitted smoothing curves and threshold effect analysis were used to describe the nonlinear relationship. Results The study comprised 8004 participants over the age of 20, including 833 reported with gallstones. Participants in the higher WWI tertile tended to have a higher gallstones prevalence. In the final adjusted model, a positive association between WWI and gallstones prevalence was observed (OR = 1.34, 95% CI: 1.20‒1.49). Participants in the highest WWI tertile had a significantly 71% higher risk of gallstones than those in the lowest WWI tertile (OR = 1.71, 95% CI: 1.35‒2.17). A nonlinear correlation was found between the WWI and gallstones prevalence, with an inflection point of 12.7. Conclusions Our study found that higher WWI levels connected with increased prevalence of gallstones. However, more prospective studies are needed to validate our findings.https://doi.org/10.1186/s12876-024-03127-9Weight-adjusted-waist indexGallstonesVisceral fatCross-sectional studyNHANES |
| spellingShingle | Si-Hua Wen Xin Tang Tao Tang Zheng-Rong Ye Association between weight-adjusted-waist index and gallstones: an analysis of the National Health and Nutrition Examination Survey BMC Gastroenterology Weight-adjusted-waist index Gallstones Visceral fat Cross-sectional study NHANES |
| title | Association between weight-adjusted-waist index and gallstones: an analysis of the National Health and Nutrition Examination Survey |
| title_full | Association between weight-adjusted-waist index and gallstones: an analysis of the National Health and Nutrition Examination Survey |
| title_fullStr | Association between weight-adjusted-waist index and gallstones: an analysis of the National Health and Nutrition Examination Survey |
| title_full_unstemmed | Association between weight-adjusted-waist index and gallstones: an analysis of the National Health and Nutrition Examination Survey |
| title_short | Association between weight-adjusted-waist index and gallstones: an analysis of the National Health and Nutrition Examination Survey |
| title_sort | association between weight adjusted waist index and gallstones an analysis of the national health and nutrition examination survey |
| topic | Weight-adjusted-waist index Gallstones Visceral fat Cross-sectional study NHANES |
| url | https://doi.org/10.1186/s12876-024-03127-9 |
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