| Summary: | An effortless and highly efficient strategy for the synthesis of ferrocene-appended azo-phenothiazines (PHz's) under ultrasound irradiation has been developed. The said protocol allows for a more environmentally friendly approach, such as operationally simple, tolerates a wide range of functional groups compared to conventional methods, and is applicable on a gram scale without additional purification or other solvent waste. The synthesized compounds 6(aa-ec) were tested for their antimicrobial activity in vitro. Off all the compounds tested, 6ca and 6da showed maximum antibacterial against S. enteric and Bacillus cereus as well as excellent antifungal activity against A. flavus and A. fumigatus.
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