Ultrasound-assisted, green and efficient synthesis of ferrocene-appended azo-phenothiazines
An effortless and highly efficient strategy for the synthesis of ferrocene-appended azo-phenothiazines (PHz's) under ultrasound irradiation has been developed. The said protocol allows for a more environmentally friendly approach, such as operationally simple, tolerates a wide range of function...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-01-01
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| Series: | Current Research in Green and Sustainable Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666086521000722 |
| _version_ | 1819102256995237888 |
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| author | Varsha Kambale Jagannath Jadhav, Ph D Pravina Piste, Ph D |
| author_facet | Varsha Kambale Jagannath Jadhav, Ph D Pravina Piste, Ph D |
| author_sort | Varsha Kambale |
| collection | DOAJ |
| description | An effortless and highly efficient strategy for the synthesis of ferrocene-appended azo-phenothiazines (PHz's) under ultrasound irradiation has been developed. The said protocol allows for a more environmentally friendly approach, such as operationally simple, tolerates a wide range of functional groups compared to conventional methods, and is applicable on a gram scale without additional purification or other solvent waste. The synthesized compounds 6(aa-ec) were tested for their antimicrobial activity in vitro. Off all the compounds tested, 6ca and 6da showed maximum antibacterial against S. enteric and Bacillus cereus as well as excellent antifungal activity against A. flavus and A. fumigatus. |
| first_indexed | 2024-12-22T01:31:41Z |
| format | Article |
| id | doaj.art-9f26f324286a4ad3b631a4c0bbeda6f7 |
| institution | Directory Open Access Journal |
| issn | 2666-0865 |
| language | English |
| last_indexed | 2024-12-22T01:31:41Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Current Research in Green and Sustainable Chemistry |
| spelling | doaj.art-9f26f324286a4ad3b631a4c0bbeda6f72022-12-21T18:43:28ZengElsevierCurrent Research in Green and Sustainable Chemistry2666-08652021-01-014100125Ultrasound-assisted, green and efficient synthesis of ferrocene-appended azo-phenothiazinesVarsha Kambale0Jagannath Jadhav, Ph D1Pravina Piste, Ph D2PG Department of Chemistry, A.S.C. College Ramanandnagar (Burli), Sangli, 416308, M.S, IndiaDepartment of Chemistry, Shivaji University, Kolhapur, 416004, M.S, IndiaPG Department of Chemistry, A.S.C. College Ramanandnagar (Burli), Sangli, 416308, M.S, India; Corresponding author.An effortless and highly efficient strategy for the synthesis of ferrocene-appended azo-phenothiazines (PHz's) under ultrasound irradiation has been developed. The said protocol allows for a more environmentally friendly approach, such as operationally simple, tolerates a wide range of functional groups compared to conventional methods, and is applicable on a gram scale without additional purification or other solvent waste. The synthesized compounds 6(aa-ec) were tested for their antimicrobial activity in vitro. Off all the compounds tested, 6ca and 6da showed maximum antibacterial against S. enteric and Bacillus cereus as well as excellent antifungal activity against A. flavus and A. fumigatus.http://www.sciencedirect.com/science/article/pii/S2666086521000722Azo-phenothiazineDiazotization reactionsUltrasound irradiationAntimicrobial activity |
| spellingShingle | Varsha Kambale Jagannath Jadhav, Ph D Pravina Piste, Ph D Ultrasound-assisted, green and efficient synthesis of ferrocene-appended azo-phenothiazines Current Research in Green and Sustainable Chemistry Azo-phenothiazine Diazotization reactions Ultrasound irradiation Antimicrobial activity |
| title | Ultrasound-assisted, green and efficient synthesis of ferrocene-appended azo-phenothiazines |
| title_full | Ultrasound-assisted, green and efficient synthesis of ferrocene-appended azo-phenothiazines |
| title_fullStr | Ultrasound-assisted, green and efficient synthesis of ferrocene-appended azo-phenothiazines |
| title_full_unstemmed | Ultrasound-assisted, green and efficient synthesis of ferrocene-appended azo-phenothiazines |
| title_short | Ultrasound-assisted, green and efficient synthesis of ferrocene-appended azo-phenothiazines |
| title_sort | ultrasound assisted green and efficient synthesis of ferrocene appended azo phenothiazines |
| topic | Azo-phenothiazine Diazotization reactions Ultrasound irradiation Antimicrobial activity |
| url | http://www.sciencedirect.com/science/article/pii/S2666086521000722 |
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