Concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case report

Abstract Background Tuberculosis (TB) remains a severe health burden worldwide. The manifestation of concurrent tuberculous cerebral and ocular involvements associated with TB is uncommon. Case presentation We report a 17-year-old girl with concurrent tuberculous cerebral and ocular involvements and...

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Main Authors: Yan-Kun Zhang, Hong-Yi Fu, Yan Guan, Yu-Jing Li, Hong-Zhong Bai
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Ophthalmology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12886-020-01504-y
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author Yan-Kun Zhang
Hong-Yi Fu
Yan Guan
Yu-Jing Li
Hong-Zhong Bai
author_facet Yan-Kun Zhang
Hong-Yi Fu
Yan Guan
Yu-Jing Li
Hong-Zhong Bai
author_sort Yan-Kun Zhang
collection DOAJ
description Abstract Background Tuberculosis (TB) remains a severe health burden worldwide. The manifestation of concurrent tuberculous cerebral and ocular involvements associated with TB is uncommon. Case presentation We report a 17-year-old girl with concurrent tuberculous cerebral and ocular involvements and visual impairment due to choroidal neovascularization. This study emphasizes the definite diagnosis with the combination of ophthalmological examination, multimodal imaging and routine tuberculosis testing, and the proper management with intravitreal anti-VEGF injection accompanied by systemic anti-tuberculosis therapy. Conclusion Combined applications of routine TB tests, fundus multimodal imaging and diagnostic therapy greatly help the clinician to establish a precise diagnosis and in monitoring the therapeutic response.
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spelling doaj.art-9f27509b801e460ab13b14ed5c2a969c2022-12-22T02:49:21ZengBMCBMC Ophthalmology1471-24152020-06-012011410.1186/s12886-020-01504-yConcurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case reportYan-Kun Zhang0Hong-Yi Fu1Yan Guan2Yu-Jing Li3Hong-Zhong Bai4Department of Ophthalmology, Hebei Chest HospitalDepartment of Tuberculosis, Hebei Chest HospitalDepartment of Ophthalmology, Hebei Chest HospitalClinical Laboratory, Hebei Chest HospitalDepartment of Radiology, Hebei Chest HospitalAbstract Background Tuberculosis (TB) remains a severe health burden worldwide. The manifestation of concurrent tuberculous cerebral and ocular involvements associated with TB is uncommon. Case presentation We report a 17-year-old girl with concurrent tuberculous cerebral and ocular involvements and visual impairment due to choroidal neovascularization. This study emphasizes the definite diagnosis with the combination of ophthalmological examination, multimodal imaging and routine tuberculosis testing, and the proper management with intravitreal anti-VEGF injection accompanied by systemic anti-tuberculosis therapy. Conclusion Combined applications of routine TB tests, fundus multimodal imaging and diagnostic therapy greatly help the clinician to establish a precise diagnosis and in monitoring the therapeutic response.http://link.springer.com/article/10.1186/s12886-020-01504-yIntraocular tuberculosisTuberculous chorioretinitisTuberculous meningitisOptical coherence tomographyChoroidal neovascularizationVascular endothelial growth factor
spellingShingle Yan-Kun Zhang
Hong-Yi Fu
Yan Guan
Yu-Jing Li
Hong-Zhong Bai
Concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case report
BMC Ophthalmology
Intraocular tuberculosis
Tuberculous chorioretinitis
Tuberculous meningitis
Optical coherence tomography
Choroidal neovascularization
Vascular endothelial growth factor
title Concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case report
title_full Concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case report
title_fullStr Concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case report
title_full_unstemmed Concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case report
title_short Concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis: a case report
title_sort concurrent tuberculous chorioretinitis with choroidal neovascularization and tuberculous meningitis a case report
topic Intraocular tuberculosis
Tuberculous chorioretinitis
Tuberculous meningitis
Optical coherence tomography
Choroidal neovascularization
Vascular endothelial growth factor
url http://link.springer.com/article/10.1186/s12886-020-01504-y
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AT yanguan concurrenttuberculouschorioretinitiswithchoroidalneovascularizationandtuberculousmeningitisacasereport
AT yujingli concurrenttuberculouschorioretinitiswithchoroidalneovascularizationandtuberculousmeningitisacasereport
AT hongzhongbai concurrenttuberculouschorioretinitiswithchoroidalneovascularizationandtuberculousmeningitisacasereport