Research progress of new antiplatelet drugs in the prevention and treatment for ischemic stroke
Nowadays, antiplatelet drugs are still the routine medication in the acute phase and in secondary prevention of ischemic stroke. Although the clinical effect of classic antiplatelet drugs, such as aspirin and clopidogrel, has been recognized, some problems still exist, such as clopidogrel resistance...
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| Format: | Article |
| Language: | English |
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Tianjin Huanhu Hospital
2013-04-01
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| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
| Subjects: | |
| Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/696 |
| _version_ | 1811308465265573888 |
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| author | Pan LI Yu-ying ZHOU |
| author_facet | Pan LI Yu-ying ZHOU |
| author_sort | Pan LI |
| collection | DOAJ |
| description | Nowadays, antiplatelet drugs are still the routine medication in the acute phase and in secondary prevention of ischemic stroke. Although the clinical effect of classic antiplatelet drugs, such as aspirin and clopidogrel, has been recognized, some problems still exist, such as clopidogrel resistance and increased bleeding risk. Therefore, new antiplatelet drugs have been studied and are incorporated into the clinical use currently. Their different pharmacokinetic and pharmacodynamic properties are good additions to the classic antiplatelet therapy, so as to overcome the limitations of the latter. This article will summarize existing clinical evidences and highlight the main features of new antiplatelet drugs, as well as listing some challenges in the use of these therapies. <br /> |
| first_indexed | 2024-04-13T09:23:39Z |
| format | Article |
| id | doaj.art-9f2809576ed9423d8c35bad59f1a905a |
| institution | Directory Open Access Journal |
| issn | 1672-6731 |
| language | English |
| last_indexed | 2024-04-13T09:23:39Z |
| publishDate | 2013-04-01 |
| publisher | Tianjin Huanhu Hospital |
| record_format | Article |
| series | Chinese Journal of Contemporary Neurology and Neurosurgery |
| spelling | doaj.art-9f2809576ed9423d8c35bad59f1a905a2022-12-22T02:52:31ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312013-04-01134273278695Research progress of new antiplatelet drugs in the prevention and treatment for ischemic strokePan LIYu-ying ZHOUNowadays, antiplatelet drugs are still the routine medication in the acute phase and in secondary prevention of ischemic stroke. Although the clinical effect of classic antiplatelet drugs, such as aspirin and clopidogrel, has been recognized, some problems still exist, such as clopidogrel resistance and increased bleeding risk. Therefore, new antiplatelet drugs have been studied and are incorporated into the clinical use currently. Their different pharmacokinetic and pharmacodynamic properties are good additions to the classic antiplatelet therapy, so as to overcome the limitations of the latter. This article will summarize existing clinical evidences and highlight the main features of new antiplatelet drugs, as well as listing some challenges in the use of these therapies. <br />http://www.cjcnn.org/index.php/cjcnn/article/view/696Platelet aggregation inhibitorsBrain ischemiaStrokeReview |
| spellingShingle | Pan LI Yu-ying ZHOU Research progress of new antiplatelet drugs in the prevention and treatment for ischemic stroke Chinese Journal of Contemporary Neurology and Neurosurgery Platelet aggregation inhibitors Brain ischemia Stroke Review |
| title | Research progress of new antiplatelet drugs in the prevention and treatment for ischemic stroke |
| title_full | Research progress of new antiplatelet drugs in the prevention and treatment for ischemic stroke |
| title_fullStr | Research progress of new antiplatelet drugs in the prevention and treatment for ischemic stroke |
| title_full_unstemmed | Research progress of new antiplatelet drugs in the prevention and treatment for ischemic stroke |
| title_short | Research progress of new antiplatelet drugs in the prevention and treatment for ischemic stroke |
| title_sort | research progress of new antiplatelet drugs in the prevention and treatment for ischemic stroke |
| topic | Platelet aggregation inhibitors Brain ischemia Stroke Review |
| url | http://www.cjcnn.org/index.php/cjcnn/article/view/696 |
| work_keys_str_mv | AT panli researchprogressofnewantiplateletdrugsinthepreventionandtreatmentforischemicstroke AT yuyingzhou researchprogressofnewantiplateletdrugsinthepreventionandtreatmentforischemicstroke |