Fingolimod effects in neuroinflammation: Regulation of astroglial glutamate transporters?
Fingolimod is an oral sphingosine-1-phosphate-receptor modulator which reduces the recirculation of immune cells and may also directly target glial cells. Here we investigate effects of fingolimod on expression of astroglial glutamate transporters under pro-inflammatory conditions. In astrocyte cell...
Main Authors: | De-Hyung Lee, Silvia Seubert, Konstantin Huhn, Lukas Brecht, Caroline Rötger, Anne Waschbisch, Johannes Schlachetzki, Alice Klausmeyer, Arthur Melms, Stefan Wiese, Jürgen Winkler, Ralf A Linker |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5342171?pdf=render |
Similar Items
-
Rapid recycling of glutamate transporters on the astroglial surface
by: Piotr Michaluk, et al.
Published: (2021-04-01) -
Age-dependent astroglial vulnerability to hypoxia and glutamate: the role for erythropoietin.
by: Ali Lourhmati, et al.
Published: (2013-01-01) -
Potential of Sodium MRI as a Biomarker for Neurodegeneration and Neuroinflammation in Multiple Sclerosis
by: Konstantin Huhn, et al.
Published: (2019-02-01) -
Central Autonomic Dysfunction Delays Recovery of Fingolimod Induced Heart Rate Slowing.
by: Max J Hilz, et al.
Published: (2015-01-01) -
Amantadine Combines Astroglial System Xc<sup>−</sup> Activation with Glutamate/NMDA Receptor Inhibition
by: Tomosuke Nakano, et al.
Published: (2019-05-01)