Degradation rates and products of fluticasone propionate in alkaline solutions
The apparent degradation rate constant of fluticasone propionate (FLT) in 0.1 M NaOH:methanol=1:1 at 37 °C was previously reported to be 0.169±0.003 h−1, and four degradation products (products 1–4) were observed in the solution. The aims of the present study were to assess the degradation rates of...
Main Authors: | Tadakazu Tokumura, Naoko Yoshida, Kanami Mori-Yasumoto, Osamu Shirota, Takuro Kurita |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-10-01
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Series: | Journal of Pharmaceutical Analysis |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2095177917300230 |
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