Genome-wide screening of tumor suppressor genes in oncogenic transformation of normal lung epithelial cells and preliminary validation in sample databases

Genome-wide screening of tumor suppressor genes in oncogenic transformation of normal lung epithelial cells and preliminary validation in sample databases

Objective To identify new human lung cancer suppressors in a genome-wide screening library during neoplastic transformation of normal human lung epithelial cells using CRISPR/Cas9-mediated genome editing, and preliminarily validate the Results in non-small cell lung cancer (NSCLC) sample databases....

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Bibliographic Details
Main Authors: ZHAO Binyu, ZHANG Junlei, WANG Jiaqi, RUAN Yan, ZHANG Yue, LIU Lianlian
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2022-03-01
Series:Di-san junyi daxue xuebao
Subjects:
neoplastic transformation
crispr/cas9
tumor suppressor genes
genome-wide screening
lung cancer
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202112095.htm

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