Premigration social adversity and autism spectrum disorder
BackgroundSeveral studies suggest significant relationships between migration and autism spectrum disorder (ASD) but there are discrepant results. Given that no studies to date have included a pathological control group, the specificity of the results in ASD can be questioned.AimsTo compare the migr...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2020-09-01
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| Series: | BJPsych Open |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2056472420000563/type/journal_article |
| _version_ | 1811157025791410176 |
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| author | Natacha Augereau Ines Lagdas Solenn Kermarrec Ludovic Gicquel Virginie Martin Jean Xavier David Cohen Michel Bouvet Anne-Catherine Rolland Sylvie Tordjman |
| author_facet | Natacha Augereau Ines Lagdas Solenn Kermarrec Ludovic Gicquel Virginie Martin Jean Xavier David Cohen Michel Bouvet Anne-Catherine Rolland Sylvie Tordjman |
| author_sort | Natacha Augereau |
| collection | DOAJ |
| description | BackgroundSeveral studies suggest significant relationships between migration and autism spectrum disorder (ASD) but there are discrepant results. Given that no studies to date have included a pathological control group, the specificity of the results in ASD can be questioned.AimsTo compare the migration experience (premigration, migratory trip, postmigration) in ASD and non-ASD pathological control groups, and study the relationships between migration and autism severity.MethodParents’ and grandparents’ migrant status was compared in 30 prepubertal boys with ASD and 30 prepubertal boys without ASD but with language disorders, using a questionnaire including Human Development Index (HDI)/Inequality-adjusted Human Development Index (IHDI) of native countries. Autism severity was assessed using the Child Autism Rating Scale, Autism Diagnostic Observation Schedule and Autism Diagnostic Interview-Revised scales.ResultsThe parents’ and grandparents’ migrant status frequency did not differ between ASD and control groups and was not associated with autism severity. The HDI/IHDI values of native countries were significantly lower for parents and grandparents of children with ASD compared with the controls, especially for paternal grandparents. Furthermore, HDI/IDHI levels from the paternal line (father and especially paternal grandparents) were significantly negatively correlated with autism severity, particularly for social interaction impairments.ConclusionsIn this study, parents’ and/or grandparents’ migrant status did not discriminate ASD and pathological control groups and did not contribute either to autism severity. However, the HDI/IHDI results suggest that social adversity-related stress experienced in native countries, especially by paternal grandparents, is potentially a traumatic experience that may play a role in ASD development. A ‘premigration theory of autism’ is then proposed. |
| first_indexed | 2024-04-10T04:59:23Z |
| format | Article |
| id | doaj.art-9f2d5a35227f4c44a7df7f8e4cdf3795 |
| institution | Directory Open Access Journal |
| issn | 2056-4724 |
| language | English |
| last_indexed | 2024-04-10T04:59:23Z |
| publishDate | 2020-09-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | BJPsych Open |
| spelling | doaj.art-9f2d5a35227f4c44a7df7f8e4cdf37952023-03-09T12:29:04ZengCambridge University PressBJPsych Open2056-47242020-09-01610.1192/bjo.2020.56Premigration social adversity and autism spectrum disorderNatacha Augereau0Ines Lagdas1Solenn Kermarrec2https://orcid.org/0000-0003-1216-8858Ludovic Gicquel3Virginie Martin4Jean Xavier5David Cohen6Michel Bouvet7Anne-Catherine Rolland8Sylvie Tordjman9https://orcid.org/0000-0002-9640-7627Pôle Hospitalo-Universitaire de Psychiatrie de l'Enfant et de l'Adolescent de Rennes (PHUPEA), Centre Hospitalier Guillaume Régnier (CHGR) and Université de Rennes 1, FranceSchool of Medicine of Rabat, University of Rabat, Marrocco; and PHUPEA, CHGR and Université de Rennes 1, FrancePHUPEA, CHGR and Université de Rennes 1, FrancePôle Hospitalo-Universitaire de Psychiatrie de l'Enfant et de l'Adolescent, Centre Hospitalier Henri Laborit and Université de Poitiers, Unité de Recherche Clinique, CAPS, Poitiers, FrancePôle Hospitalo-Universitaire de Psychiatrie de l'Enfant et de l'Adolescent, Centre Hospitalier Henri Laborit; and Université de Poitiers, Unité de Recherche Clinique, CAPS, FranceCentre Hospitalier Spécialisé Henri Laborit, Poitiers; and CNRS UMR 7295 Centre de Recherches sur la Cognition et l'Apprentissage, Poitiers, FranceDepartment of Child and Adolescent Psychiatry, AP-HP, GH Pitié-Salpétrière, CNRS FRE 2987, University Pierre and Marie Curie, FranceService Hospitalo-Universitaire de Psychiatrie de l'Enfant et de l'Adolescent de Reims, Pôle Femme-Parents-Enfant, FranceService Hospitalo-Universitaire de Psychiatrie de l'Enfant et de l'Adolescent de Reims, Pôle Femme-Parents-Enfant, FrancePôle Hospitalo-Universitaire de Psychiatrie de l'Enfant et de l'Adolescent (PHUPEA), Centre Hospitalier Guillaume Régnier (CHGR) and Université de Rennes 1; and Integrative Neuroscience and Cognition Center (INCC), CNRS UMR 8002 and Université de Paris, FranceBackgroundSeveral studies suggest significant relationships between migration and autism spectrum disorder (ASD) but there are discrepant results. Given that no studies to date have included a pathological control group, the specificity of the results in ASD can be questioned.AimsTo compare the migration experience (premigration, migratory trip, postmigration) in ASD and non-ASD pathological control groups, and study the relationships between migration and autism severity.MethodParents’ and grandparents’ migrant status was compared in 30 prepubertal boys with ASD and 30 prepubertal boys without ASD but with language disorders, using a questionnaire including Human Development Index (HDI)/Inequality-adjusted Human Development Index (IHDI) of native countries. Autism severity was assessed using the Child Autism Rating Scale, Autism Diagnostic Observation Schedule and Autism Diagnostic Interview-Revised scales.ResultsThe parents’ and grandparents’ migrant status frequency did not differ between ASD and control groups and was not associated with autism severity. The HDI/IHDI values of native countries were significantly lower for parents and grandparents of children with ASD compared with the controls, especially for paternal grandparents. Furthermore, HDI/IDHI levels from the paternal line (father and especially paternal grandparents) were significantly negatively correlated with autism severity, particularly for social interaction impairments.ConclusionsIn this study, parents’ and/or grandparents’ migrant status did not discriminate ASD and pathological control groups and did not contribute either to autism severity. However, the HDI/IHDI results suggest that social adversity-related stress experienced in native countries, especially by paternal grandparents, is potentially a traumatic experience that may play a role in ASD development. A ‘premigration theory of autism’ is then proposed.https://www.cambridge.org/core/product/identifier/S2056472420000563/type/journal_articleAutism spectrum disorder (ASD)migrationhuman development index (HDI/IHDI)social adversitypremigration stress |
| spellingShingle | Natacha Augereau Ines Lagdas Solenn Kermarrec Ludovic Gicquel Virginie Martin Jean Xavier David Cohen Michel Bouvet Anne-Catherine Rolland Sylvie Tordjman Premigration social adversity and autism spectrum disorder BJPsych Open Autism spectrum disorder (ASD) migration human development index (HDI/IHDI) social adversity premigration stress |
| title | Premigration social adversity and autism spectrum disorder |
| title_full | Premigration social adversity and autism spectrum disorder |
| title_fullStr | Premigration social adversity and autism spectrum disorder |
| title_full_unstemmed | Premigration social adversity and autism spectrum disorder |
| title_short | Premigration social adversity and autism spectrum disorder |
| title_sort | premigration social adversity and autism spectrum disorder |
| topic | Autism spectrum disorder (ASD) migration human development index (HDI/IHDI) social adversity premigration stress |
| url | https://www.cambridge.org/core/product/identifier/S2056472420000563/type/journal_article |
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