Associations between trunk-to-peripheral fat ratio and cardiometabolic risk factors in elderly Japanese men: baseline data from the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study
Abstract Background Body mass-independent parameters might be more appropriate for assessing cardiometabolic abnormalities than weight-dependent indices in Asians who have relatively high visceral adiposity but low body fat. Dual-energy X-ray absorptiometry (DXA)-measured trunk-to-peripheral fat rat...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Komiyama Printing Co. Ltd
2021-03-01
|
| Series: | Environmental Health and Preventive Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12199-021-00959-9 |
| _version_ | 1818015316570013696 |
|---|---|
| author | Katsuyasu Kouda Yuki Fujita Kumiko Ohara Takahiro Tachiki Junko Tamaki Akiko Yura Jong-Seong Moon Etsuko Kajita Kazuhiro Uenishi Masayuki Iki |
| author_facet | Katsuyasu Kouda Yuki Fujita Kumiko Ohara Takahiro Tachiki Junko Tamaki Akiko Yura Jong-Seong Moon Etsuko Kajita Kazuhiro Uenishi Masayuki Iki |
| author_sort | Katsuyasu Kouda |
| collection | DOAJ |
| description | Abstract Background Body mass-independent parameters might be more appropriate for assessing cardiometabolic abnormalities than weight-dependent indices in Asians who have relatively high visceral adiposity but low body fat. Dual-energy X-ray absorptiometry (DXA)-measured trunk-to-peripheral fat ratio is one such body mass-independent index. However, there are no reports on relationships between DXA-measured regional fat ratio and cardiometabolic risk factors targeting elderly Asian men. Methods We analyzed cross-sectional data of 597 elderly men who participated in the baseline survey of the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study, a community-based single-center prospective cohort study conducted in Japan. Whole-body fat and regional fat were measured with a DXA scanner. Trunk-to-appendicular fat ratio (TAR) was calculated as trunk fat divided by appendicular fat (sum of arm and leg fat), and trunk-to-leg fat ratio (TLR) as trunk fat divided by leg fat. Results Both TAR and TLR in the group of men who used ≥ 1 medication for hypertension, dyslipidemia, or diabetes (“user group”; N = 347) were significantly larger than those who did not use such medication (“non-user group”; N = 250) (P < 0.05). After adjusting for potential confounding factors including whole-body fat, both TAR and TLR were significantly associated with low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglyceride, fasting serum insulin, and the insulin resistance index in the non-user group and non-overweight men in the non-user group (N = 199). Conclusion The trunk-to-peripheral fat ratio was associated with cardiometabolic risk factors independently of whole-body fat mass. Parameters of the fat ratio may be useful for assessing cardiometabolic risk factors, particularly in underweight to normal-weight populations. |
| first_indexed | 2024-04-14T06:55:27Z |
| format | Article |
| id | doaj.art-9f2e142da73147c292291a360038d8e1 |
| institution | Directory Open Access Journal |
| issn | 1342-078X 1347-4715 |
| language | English |
| last_indexed | 2024-04-14T06:55:27Z |
| publishDate | 2021-03-01 |
| publisher | Komiyama Printing Co. Ltd |
| record_format | Article |
| series | Environmental Health and Preventive Medicine |
| spelling | doaj.art-9f2e142da73147c292291a360038d8e12022-12-22T02:06:54ZengKomiyama Printing Co. LtdEnvironmental Health and Preventive Medicine1342-078X1347-47152021-03-0126111210.1186/s12199-021-00959-9Associations between trunk-to-peripheral fat ratio and cardiometabolic risk factors in elderly Japanese men: baseline data from the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) studyKatsuyasu Kouda0Yuki Fujita1Kumiko Ohara2Takahiro Tachiki3Junko Tamaki4Akiko Yura5Jong-Seong Moon6Etsuko Kajita7Kazuhiro Uenishi8Masayuki Iki9Department of Hygiene and Public Health, Kansai Medical UniversityDepartment of Public Health, Kindai University Faculty of MedicineDepartment of Public Health, Kindai University Faculty of MedicineChukyo Gakuin University Faculty of NursingDepartment of Hygiene and Public Health, Osaka Medical CollegeDepartment of Public Health, Kindai University Faculty of MedicineDepartment of Nursing, Kio UniversityChukyo Gakuin University Faculty of NursingLaboratory of Physiological Nutrition, Kagawa Nutrition UniversityDepartment of Public Health, Kindai University Faculty of MedicineAbstract Background Body mass-independent parameters might be more appropriate for assessing cardiometabolic abnormalities than weight-dependent indices in Asians who have relatively high visceral adiposity but low body fat. Dual-energy X-ray absorptiometry (DXA)-measured trunk-to-peripheral fat ratio is one such body mass-independent index. However, there are no reports on relationships between DXA-measured regional fat ratio and cardiometabolic risk factors targeting elderly Asian men. Methods We analyzed cross-sectional data of 597 elderly men who participated in the baseline survey of the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study, a community-based single-center prospective cohort study conducted in Japan. Whole-body fat and regional fat were measured with a DXA scanner. Trunk-to-appendicular fat ratio (TAR) was calculated as trunk fat divided by appendicular fat (sum of arm and leg fat), and trunk-to-leg fat ratio (TLR) as trunk fat divided by leg fat. Results Both TAR and TLR in the group of men who used ≥ 1 medication for hypertension, dyslipidemia, or diabetes (“user group”; N = 347) were significantly larger than those who did not use such medication (“non-user group”; N = 250) (P < 0.05). After adjusting for potential confounding factors including whole-body fat, both TAR and TLR were significantly associated with low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglyceride, fasting serum insulin, and the insulin resistance index in the non-user group and non-overweight men in the non-user group (N = 199). Conclusion The trunk-to-peripheral fat ratio was associated with cardiometabolic risk factors independently of whole-body fat mass. Parameters of the fat ratio may be useful for assessing cardiometabolic risk factors, particularly in underweight to normal-weight populations.https://doi.org/10.1186/s12199-021-00959-9Body fat distributionDensitometryEpidemiologyRisk factors |
| spellingShingle | Katsuyasu Kouda Yuki Fujita Kumiko Ohara Takahiro Tachiki Junko Tamaki Akiko Yura Jong-Seong Moon Etsuko Kajita Kazuhiro Uenishi Masayuki Iki Associations between trunk-to-peripheral fat ratio and cardiometabolic risk factors in elderly Japanese men: baseline data from the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study Environmental Health and Preventive Medicine Body fat distribution Densitometry Epidemiology Risk factors |
| title | Associations between trunk-to-peripheral fat ratio and cardiometabolic risk factors in elderly Japanese men: baseline data from the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study |
| title_full | Associations between trunk-to-peripheral fat ratio and cardiometabolic risk factors in elderly Japanese men: baseline data from the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study |
| title_fullStr | Associations between trunk-to-peripheral fat ratio and cardiometabolic risk factors in elderly Japanese men: baseline data from the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study |
| title_full_unstemmed | Associations between trunk-to-peripheral fat ratio and cardiometabolic risk factors in elderly Japanese men: baseline data from the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study |
| title_short | Associations between trunk-to-peripheral fat ratio and cardiometabolic risk factors in elderly Japanese men: baseline data from the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study |
| title_sort | associations between trunk to peripheral fat ratio and cardiometabolic risk factors in elderly japanese men baseline data from the fujiwara kyo osteoporosis risk in men formen study |
| topic | Body fat distribution Densitometry Epidemiology Risk factors |
| url | https://doi.org/10.1186/s12199-021-00959-9 |
| work_keys_str_mv | AT katsuyasukouda associationsbetweentrunktoperipheralfatratioandcardiometabolicriskfactorsinelderlyjapanesemenbaselinedatafromthefujiwarakyoosteoporosisriskinmenformenstudy AT yukifujita associationsbetweentrunktoperipheralfatratioandcardiometabolicriskfactorsinelderlyjapanesemenbaselinedatafromthefujiwarakyoosteoporosisriskinmenformenstudy AT kumikoohara associationsbetweentrunktoperipheralfatratioandcardiometabolicriskfactorsinelderlyjapanesemenbaselinedatafromthefujiwarakyoosteoporosisriskinmenformenstudy AT takahirotachiki associationsbetweentrunktoperipheralfatratioandcardiometabolicriskfactorsinelderlyjapanesemenbaselinedatafromthefujiwarakyoosteoporosisriskinmenformenstudy AT junkotamaki associationsbetweentrunktoperipheralfatratioandcardiometabolicriskfactorsinelderlyjapanesemenbaselinedatafromthefujiwarakyoosteoporosisriskinmenformenstudy AT akikoyura associationsbetweentrunktoperipheralfatratioandcardiometabolicriskfactorsinelderlyjapanesemenbaselinedatafromthefujiwarakyoosteoporosisriskinmenformenstudy AT jongseongmoon associationsbetweentrunktoperipheralfatratioandcardiometabolicriskfactorsinelderlyjapanesemenbaselinedatafromthefujiwarakyoosteoporosisriskinmenformenstudy AT etsukokajita associationsbetweentrunktoperipheralfatratioandcardiometabolicriskfactorsinelderlyjapanesemenbaselinedatafromthefujiwarakyoosteoporosisriskinmenformenstudy AT kazuhirouenishi associationsbetweentrunktoperipheralfatratioandcardiometabolicriskfactorsinelderlyjapanesemenbaselinedatafromthefujiwarakyoosteoporosisriskinmenformenstudy AT masayukiiki associationsbetweentrunktoperipheralfatratioandcardiometabolicriskfactorsinelderlyjapanesemenbaselinedatafromthefujiwarakyoosteoporosisriskinmenformenstudy |