Urine microRNA as potential biomarkers of autosomal dominant polycystic kidney disease progression: description of miRNA profiles at baseline.

Urine microRNA as potential biomarkers of autosomal dominant polycystic kidney disease progression: description of miRNA profiles at baseline.

Autosomal dominant polycystic kidney disease (ADPKD) is clinically heterogenic. Biomarkers are needed to predict prognosis and guide management. We aimed to profile microRNA (miRNA) in ADPKD to gain molecular insight and evaluate biomarker potential.Small-RNA libraries were generated from urine spec...

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Bibliographic Details
Main Authors: Iddo Z Ben-Dov, Ying-Cai Tan, Pavel Morozov, Patricia D Wilson, Hanna Rennert, Jon D Blumenfeld, Thomas Tuschl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3906110?pdf=render

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http://europepmc.org/articles/PMC3906110?pdf=render

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