Rare Mutations in CCDC7 Contribute to Early-Onset Preeclampsia by Inhibiting Trophoblast Migration and Invasion

Rare Mutations in CCDC7 Contribute to Early-Onset Preeclampsia by Inhibiting Trophoblast Migration and Invasion

Rare gene variants have been found to play a role in complex disorders. Preeclampsia, and especially early-onset preeclampsia, has a strong genetic link. However, the role of rare variants in the offspring of mothers with preeclampsia remains unclear. In this study, whole-exome sequencing (WES) was...

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Bibliographic Details
Main Authors: Hu Tan, Li Yu, Jingsi Chen, Xiaoyi Wang, Fang He, Lin Yu, Lili Du, Dunjin Chen
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Journal of Personalized Medicine
Subjects:
early-onset preeclampsia
CCDC7
rare variants
trophoblast
migration and invasion
Online Access:https://www.mdpi.com/2075-4426/14/3/253

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