Oral ulcer as presentation of cavitating pulmonary tuberculosis
Tuberculosis is an indolent infection that can invade any organ. Although the most frequent form of presentation is pulmonary, it can have an extra-pulmonary presentation, including rare cases of oral tuberculosis.We present a clinical case of a 44 year-old man, active smoker, with an ulcerated lesi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-01-01
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| Series: | IDCases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250920302845 |
| _version_ | 1818728208445472768 |
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| author | Joana Fragoso Mariana Marques Oliveira Celina Gonçalves Josefina Méndez Rui Sarmento-Castro |
| author_facet | Joana Fragoso Mariana Marques Oliveira Celina Gonçalves Josefina Méndez Rui Sarmento-Castro |
| author_sort | Joana Fragoso |
| collection | DOAJ |
| description | Tuberculosis is an indolent infection that can invade any organ. Although the most frequent form of presentation is pulmonary, it can have an extra-pulmonary presentation, including rare cases of oral tuberculosis.We present a clinical case of a 44 year-old man, active smoker, with an ulcerated lesion on the posterior third of the tongue, initially interpreted as a probable neoplasm. The pathological study of the biopsy performed on the lesion, showed alterations compatible with a chronic granulomatous process and the presence of acid-fast bacilli. The concomitant diagnosis of pulmonary tuberculosis was made in a subsequent study. The patient started therapy with isoniazid, rifampin, pyrazinamide and ethambutol with complete resolution of the oral lesion and pulmonary tuberculosis. This case exemplifies the importance of including tuberculosis in the differential diagnosis of ulcerated and neoformative lesions and the value of performing a microbiological study alongside the pathological one. |
| first_indexed | 2024-12-17T22:26:20Z |
| format | Article |
| id | doaj.art-9f37305bc72b4159a926bedec09cbbe1 |
| institution | Directory Open Access Journal |
| issn | 2214-2509 |
| language | English |
| last_indexed | 2024-12-17T22:26:20Z |
| publishDate | 2020-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj.art-9f37305bc72b4159a926bedec09cbbe12022-12-21T21:30:20ZengElsevierIDCases2214-25092020-01-0122e00976Oral ulcer as presentation of cavitating pulmonary tuberculosisJoana Fragoso0Mariana Marques Oliveira1Celina Gonçalves2Josefina Méndez3Rui Sarmento-Castro4Serviço de Doenças Infeciosas do Centro Hospitalar Universitário do Porto, Portugal; Corresponding author at: Serviço de Doenças Infeciosas do Centro Hospitalar Universitário do Porto, EPE, Largo Abel Salazar, 4099-001, Porto, Portugal.Serviço de Anatomia Patológica do Centro Hospitalar Universitário do Porto, PortugalServiço de Doenças Infeciosas do Centro Hospitalar Universitário do Porto, Portugal; Serviço de Cuidados Intensivos do Centro Hospitalar Universitário do Porto, PortugalServiço de Doenças Infeciosas do Centro Hospitalar Universitário do Porto, PortugalServiço de Doenças Infeciosas do Centro Hospitalar Universitário do Porto, PortugalTuberculosis is an indolent infection that can invade any organ. Although the most frequent form of presentation is pulmonary, it can have an extra-pulmonary presentation, including rare cases of oral tuberculosis.We present a clinical case of a 44 year-old man, active smoker, with an ulcerated lesion on the posterior third of the tongue, initially interpreted as a probable neoplasm. The pathological study of the biopsy performed on the lesion, showed alterations compatible with a chronic granulomatous process and the presence of acid-fast bacilli. The concomitant diagnosis of pulmonary tuberculosis was made in a subsequent study. The patient started therapy with isoniazid, rifampin, pyrazinamide and ethambutol with complete resolution of the oral lesion and pulmonary tuberculosis. This case exemplifies the importance of including tuberculosis in the differential diagnosis of ulcerated and neoformative lesions and the value of performing a microbiological study alongside the pathological one.http://www.sciencedirect.com/science/article/pii/S2214250920302845Pulmonary tuberculosisTuberculous oral ulcerMycobacterium tuberculosis |
| spellingShingle | Joana Fragoso Mariana Marques Oliveira Celina Gonçalves Josefina Méndez Rui Sarmento-Castro Oral ulcer as presentation of cavitating pulmonary tuberculosis IDCases Pulmonary tuberculosis Tuberculous oral ulcer Mycobacterium tuberculosis |
| title | Oral ulcer as presentation of cavitating pulmonary tuberculosis |
| title_full | Oral ulcer as presentation of cavitating pulmonary tuberculosis |
| title_fullStr | Oral ulcer as presentation of cavitating pulmonary tuberculosis |
| title_full_unstemmed | Oral ulcer as presentation of cavitating pulmonary tuberculosis |
| title_short | Oral ulcer as presentation of cavitating pulmonary tuberculosis |
| title_sort | oral ulcer as presentation of cavitating pulmonary tuberculosis |
| topic | Pulmonary tuberculosis Tuberculous oral ulcer Mycobacterium tuberculosis |
| url | http://www.sciencedirect.com/science/article/pii/S2214250920302845 |
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